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How effective is mHealth-supported home-based post-knee arthroplasty rehabilitation in improving knee function and continuum of care: protocol of an open label randomised controlled trial from India

Por: Girotra · S. · Shrivastava · P. · Kumar · A. · Madan · R. · Grover · S. · Batra · S. · Garg · B. · Praveen · D. · Chatterjee · S. · Kasotia · A. · Biswas · S. · Soni · M. · Gara · S. · Malhotra · R. · Maddison · R. · Devasenapathy · N.
Introduction

Monitoring physical rehabilitation is an essential component of patient recovery after knee arthroplasty. Monitoring can be remote, or clinic based. In India, unsupervised home-based physical rehabilitation is a common practice, but there is a lack of evidence to demonstrate the effectiveness of remote monitoring. Therefore, we developed and piloted a mobile application (TeleREhabilitation after knee ArThroplasty app) based on behaviour design thinking to support the recovery period. This trial aims to compare the effectiveness, acceptability, cost and safety of this app-supported home-based intervention against usual care using an open label, 1:1 individual randomised superiority trial at two tertiary care hospitals in India.

Methods and analysis

Consecutive adults undergoing partial or total, unilateral or bilateral knee arthroplasty who can use a smart phone will be invited to participate in this trial. Consenting individuals will be randomised to either an app-supported intervention or a usual home-based rehabilitation which typically consists of provision of oral or written instructions at discharge and follow-up check-up with the surgeon or physiotherapist at their discretion or as per individual need. We aim to recruit 300 individuals over a period of eighteen months. The primary objective is to compare patient-reported knee function between the two groups at 3 and 6 months postsurgery. Secondary objectives are to compare patient-reported outcomes (pain and activity), performance-based outcomes (lower limb strength and knee function), resource utilisation and quality of life. Fidelity of implementation, end-user experiences and challenges in implementing this intervention will be measured using both quantitative and qualitative methods. Quantitative data will be analysed in Stata, and group comparisons will be done using mixed effect linear regression. A mixed-methods approach will be used to analyse and interpret the process evaluation data. A modified intention-to-treat approach will be taken, which includes all those who were randomised irrespective of their adherence to trial protocol if they had at least one follow-up visit after enrolment.

Ethics and dissemination

The protocol has been approved by the ethics committees of the sponsor institute (The George Institute for Global Health) and the two clinical sites (All India Institute for Medical Sciences, Delhi & Indraprastha Apollo Hospitals, Delhi). The results will be disseminated via peer-reviewed publications, conference presentations and via plain language newsletters to the trial participants.

Trial registration number

CTRI/2024/06/068838.

Effectiveness of a home-based physical exercise intervention in patients with fragility fractures on functional independence and hospital readmissions: a protocol for a randomised controlled trial

Por: Segura-Ruiz · R. · Ruiz-Canete · M. · Munoz-Alonso · A. · Rivas-Cruces · C. · Serrano-Lazaro · P. · Armenteros-Ortiz · P. J. · Hidalgo-Lopezosa · P. · Lamberti · N. · Manfredini · F. · Lopez-Soto · P. J.
Introduction

Patients with fragility fractures are two times as likely to suffer future fractures as their peers who have not suffered a fracture. In addition, 40% of those who suffer fragility fractures do not recover their level of functioning in terms of activities of daily living after 1 year. The present study aims to verify the hypothesis that a semipersonalised home-based exercise intervention may improve patients’ independence and reduce the number of hospital admissions compared with usual care for a population that suffers fragility fractures.

Methods and analysis

This parallel-arm single-blinded randomised-controlled trial will take place at the University of Cordoba (Spain) between September 2022 and September 2024. Patients aged >50 years old who have undergone surgery for a fragility hip fracture and who were prefracture independent (Barthel index (BI)>60) will be invited to participate. Patients will be excluded if they present a different type of fracture, mild or greater cognitive impairment or contraindication to exercise training. Patients will then be randomised into exercise or usual care group. The former will receive a daily walking appointment (number of steps to be completed inside home, interspersed with sit-to-stand movements) with the total volume increasing weekly. The latter will receive the usual care. The outcomes, collected at baseline, at the end of training (3 months) and at follow-up (6 months) by blinded operators will include the BI and number of readmissions (primary outcomes) and quality of life, exercise capacity, strength, cognitive status, bone mineral density and laboratory biomarkers (secondary outcomes). Variables related to quality of life, cognitive status, laboratory markers and densitometry will also be analysed.

Ethics and dissemination

The research ethics committee of the province of Cordoba approved the project (number 326; date 28 July 2021). Patients who meet the eligibility criteria will receive a patient information document and the consent form and will be encouraged to ask any questions. The proposed research respects the fundamental principles of the Declaration of Helsinki, the Council of Europe Declaration on Human Rights and Biomedicine, the UNESCO Universal Declaration on the Human Genome and Human Rights, and the Oviedo Council on Human Rights and Biomedicine. The data obtained in this study will be confidential. They will be treated by the Organic Law 3/2018, of 5 December, on the Protection of Personal Data and Guarantee of Digital Rights, keeping it strictly confidential and not accessible to unauthorised third parties, and the Regulation (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016 on Data Protection (RGPD). Written informed consent will be obtained from all the participants. The study’s results will be published in peer-reviewed journals and presented at scientific congresses worldwide. The results will also be disseminated through patient advocacy group newsletters and social media platforms. Patient partners will help select the appropriate channels and develop plain-language summaries tailored to their communities’ needs.

Trial registration number

ClinicalTrials.gov ID: NCT04934358 (registration date: 14 June 2021).

NuPOWER (Nuwiq for Perioperative management Of patients With haemophilia A on Emicizumab Regular prophylaxis): protocol for an open-label, single-arm, multicentre study

Por: Srivastava · A. · Kanny · A. · Langer · F. · Kubicek-Hofmann · C. · Alvarez Roman · M. T. · Nunez Vazquez · R. · Boban · A. · Dejanova-Ilijevska · V. · Miljic · P. · Garcia · J. · Halimeh · S. · Drillaud · N. · Valentin · J.-B. · Mancuso · M. E. · Castaman · G. · Santoro · R. C. · Leht
Introduction

Despite the known haemostatic action of emicizumab (Hemlibra) in haemophilia A patients, its role in the prevention and control of bleeding in high-demand haemostatic situations, such as major surgery, remains to be determined. Patients receiving regular emicizumab prophylaxis often require concomitant factor VIII (FVIII) therapy during major surgery to prevent uncontrolled bleeding and to promote postoperative healing. However, there are limited prospective surgical data relating to concomitant FVIII and emicizumab use. Simoctocog alfa (Nuwiq) is a B-domain deleted recombinant FVIII produced in a human cell line without chemical modification or protein fusion with proven efficacy as surgical prophylaxis in adult and paediatric patients. The Nuwiq for Perioperative management Of patients With haemophilia A on Emicizumab Regular prophylaxis (NuPOWER) study aims to examine perioperative efficacy and safety of simoctocog alfa in haemophilia A patients on emicizumab prophylaxis undergoing major surgery.

Methods and analysis

NuPOWER is a prospective, open-label, single-arm, multicentre study that will be conducted at approximately 15 centres worldwide. Up to 28 male patients ≥12 years with severe haemophilia A and no FVIII inhibitors will be recruited. All patients must be receiving regular emicizumab prophylaxis and scheduled to undergo a major surgical procedure during which concomitant simoctocog alfa will be administered. The primary endpoint is the overall haemostatic efficacy of simoctocog alfa, adjudicated by an independent data monitoring committee using a pre-defined algorithm, and will consider intraoperative and postoperative efficacy assessments by the surgeon and investigator, respectively. Secondary endpoints include intraoperative haemostatic efficacy, postoperative haemostatic efficacy, number of allogeneic blood products transfused, perioperative FVIII plasma levels (as measured by FVIII activity) and thrombin generation, and safety parameters. In the era of non-factor therapy, NuPOWER will generate valuable prospective data on concomitant use of simoctocog alfa and emicizumab prophylaxis in patients with severe haemophilia A undergoing major surgery.

Ethics and dissemination

Ethical approval has been received from institutional review boards/independent ethics committees, and the study will be conducted in compliance with the Declaration of Helsinki. This work will be disseminated by publication of peer-reviewed manuscripts and presentations at scientific meetings.

Trial registration number

CT EU 2022-502060-21-00; NCT05935358.

Exploring the Causes, Immediate Responses and Preventive Measures of Needle Stick Injuries Among Healthcare Workers: A Qualitative Evidence Synthesis

ABSTRACT

Aim

To combine, synthesise, and interpret qualitative evidence from studies exploring the causes, immediate responses, and preventive measures of needle stick injuries from the perspective of healthcare workers.

Design and Methods

In this qualitative evidence synthesis, the qualitative data from the included studies were synthesised to identify overarching themes. The Preferred Reporting Items for Systematic Reviews and Meta-analysis flowchart, Joanna Briggs Institute tool, and Enhancing Transparency in Reporting the Synthesis of Qualitative Research checklist were used in the meta-synthesis process.

Data Sources

The MEDLINE, Cumulative Index to Nursing and Allied Health Literature, Web of Science, ProQuest, ClinicalKey and Scopus databases were searched between December 14 and December 31, 2024 for studies published between January 2000 and December 2024.

Results

Nine primary research studies were included and the following themes were identified: unpredicted patient movement, casual attitude, recapping, excessive workload, scarcity of article or safety equipment, inadequate training or experience, vigilance, ongoing training, nurturing workplace culture, emotional response, re-living the injury and fear of reprimand.

Conclusion

Needle stick injuries result from a complex interplay of individual, administrative, engineering, and environmental factors, but there are potential solutions to address these issues.

Implications for the Profession and/or Patient Care

Policymakers in healthcare settings would benefit greatly from an understanding of the causes, immediate responses, and preventive aspects of needle stick injuries. These findings can direct the creation of focused interventions and safety procedures by identifying important risk variables and useful coping mechanisms.

Impact

The causes, immediate responses, and preventive measures of needle stick injuries were explored. Findings can help develop protocols to lower needle stick injury rates and increase worker safety.

Reporting Method

ENTREQ guidelines.

Patient or Public Contribution

This research is a systematic review of published peer-reviewed studies.

Clinical Registration

PROSPERO registration number: CRD42024620673.

Model-based pharmacoeconomic analysis of anti-VEGF strategies for neovascular age-related macular degeneration: a value-based comparison of real-world administration approaches

Objectives

To evaluate the cost-effectiveness of anti-vascular endothelial growth factor (VEGF) treatments for neovascular age-related macular degeneration (nAMD) using a value-based model that considers drug durability, dosing regimens and real-world administration strategies, including safe vial fractionation.

Design and setting

Model-based pharmacoeconomic analysis using data from randomised clinical trials and network meta-analyses. Analysis conducted from the payer perspective using cost data from the Spanish National Health System.

Methods

A model-based analysis compared five anti-VEGF agents—innovator and biosimilar ranibizumab, aflibercept 2 mg, brolucizumab and faricimab—across three dosing regimens: fixed, Pro Re Nata and Treat-and-Extend (TAE). Administration formats included single-use vials, prefilled syringes and vial fractionation (VF), with or without dead-space-free (DSF) syringes to minimise waste. The primary outcome was cost per optimal responder, defined as a patient gaining ≥15 Early Treatment Diabetic Retinopathy Study (ETDRS) letters, with and without adverse events. Cost-effectiveness was evaluated using Number Needed to Treat (NNT), Net Efficacy Adjusted for Risk-NNT (adjusted for safety) and incremental cost-effectiveness ratios. Secondary outcomes included the number of treated patients and optimal responders achievable within a fixed 1 000 000 budget.

Results

The most cost-effective strategy was aflibercept 2 mg under a TAE regimen using DSF VF, with a total cost of 6214 per patient and a cost per optimal responder of 27 155. Under a fixed budget of 1 000 000, this approach allowed treatment of 160 patients, yielding 36 optimal responders. Faricimab with DSF VF ranked second, with a total cost of 5847 and a cost per optimal responder of 28 652, treating 171 patients and achieving 34 responders. In contrast, single-use vials without VF led to substantially higher total costs (eg, 11 305 for aflibercept TAE) and lower treatment capacity (eg, 88 patients treated).

Conclusions

This model demonstrates that combining durable agents, extended dosing intervals and optimised delivery strategies (eg, prefilled syringes and DSF VF) can substantially improve the cost-effectiveness and sustainability of anti-VEGF therapy in public health systems.

Changes in prescription patterns of antidiabetic medication in patients newly diagnosed with type 2 diabetes in Spain: an observational study

Por: Cea-Soriano · L. · Moreno · A. · Calonge · M. · Rivas · A. · Pulido-Manzanero · J. · Colchero · M. C. · Artola · S. · Serrano · R. · Franch-Nadal · J. · Regidor · E. · the PRECOZIN Study Group · Adan · Almanzar · Alonso · Alonso · Alonso · Alvarez · Alvarez · Amoros · Araujo · Arbide
Objective

To estimate the frequency of antidiabetic prescriptions in type 2 diabetes mellitus (T2DM) in Spain and describe changes in prescription patterns between 2018–2022 and 2023-2024.

Design

Observational study.

Participants

Patients from primary care centres newly diagnosed with T2DM in 2018–2022 and 2023–2024.

Primary and secondary outcomes

In each period, the prescription frequency of an antidiabetic medication at the diagnosis of T2DM was calculated and subsequently subdivided into monotherapy and combination therapy. The prescription frequency of the most common antidiabetic drugs was also calculated. Calculations were made for the entire group of subjects and stratified by sex and age (under 60 years and 60 years or older). Comparison of the frequencies between the two periods was performed using the chi-square test.

Results

In 2018–2022 and 2023–2024, 78.4% and 88.9% of patients, respectively, were prescribed an antidiabetic medication. The prescription frequencies for monotherapy and combination therapy were 66.1% and 33.9% in the first period and 57.4% and 42.6% in the second. The prescription frequencies for metformin as monotherapy and combination therapy were 57.4% and 27.8% in the first period and 46.6% and 39.8% in the second. Prescribing metformin with sodium-glucose cotransporter-2 inhibitors (SGLT2i) and/or glucagon-like peptide receptor 1 agonists (GLP1a) was the most frequent combination therapy: 12.8% in 2018–2022 and 29.5% in 2023–2024. With a few exceptions, the prescribing pattern was similar by sex and age. The difference between the prescribing distributions in the two periods is significant.

Conclusion

Antidiabetic medication prescribing at the diagnosis of T2DM was high. Most prescriptions contained metformin. Monotherapy decreased in 2023–2024 compared with 2018–2022, while combination therapy increased due to increased prescriptions of metformin with SGLT2i and/or GLP1a.

Comparison of treatment efficacy between topical insulin and autologous serum in persistent epithelial defects: a randomised controlled trial protocol in Spain

Por: Arriola-Villalobos · P. · Burgos-Blasco · B. · Ascaso-del-Rio · A. · Medina-Ramirez · L. · Rivas · A. B. · Perez-Macias · N. · Diaz-Valle · D. · Portoles-Perez · A.
Background

Persistent epithelial defect (PED) management can be challenging. First line of treatment includes lubrication, bandage contact lenses and punctal plugs. The second line of treatment includes autologous serum (AS). Topical insulin has been shown to be safe for topical use and improve corneal epithelial healing. Therefore, a controlled clinical trial (control group with current standard treatment, ie, AS) multicentre, randomised and with a blind third observer will be conducted to evaluate the efficacy and safety of the use of insulin eye-drops in the treatment of PED.

Methods and analysis

A preselection of patients with epithelial defect after 1 week of treatment will be made and blood tests will be obtained in order to dispense AS if necessary. After 2 weeks of standard treatment, if the PED persists and the patient meets criteria, patients will be enrolled after signing an informed consent form. Patients will be randomly allocated to receive either insulin (1 UI/mL, 4 times a day) or AS (20%, 5–6 times a day) eye-drops for 3 months. 234 patients will be included, 117 in each treatment group. The main variable (PED size) will be obtained from slit-lamp photographs, an objective and easily quantifiable variable which will be evaluated by a blinded investigator (third observer). Patients will be examined every 3–5 days until week 4 of study treatment and once a week until 6 weeks, to continue with a visit every 2 weeks until reaching 3 months of follow-up. Primary endpoints are: complete epithelialisation, epithelialisation rate (initial defect area/days until epithelialisation) and time until complete closure.

Ethics and dissemination

Ethical approval has been obtained from Hospital Clinico San Carlos in Madrid and Agencia Española del Medicamento y Productos Sanitarios (AEMPS). The findings will be disseminated in peer-reviewed publications and presentations at meetings.

Trial registration number

EudraCT 2022-003589-19.

Ayuda asistencial a los trabajadores ancianos al retirarse de sus oficios en un hospital sevillano en el Antiguo Régimen español y su proyección en Lima, Virreinato del Perú

Este trabajo tiene por objetivo  estudiar la ayuda asistencial de trabajadores hospitalarios  ancianos en una institución administrada por religiosos en el Antiguo Régimen español. El caso de estudio es el hospital de las Cinco Llagas de Sevilla. La metodología aplicada fue la heurística y la hermenéutica de las fuentes históricas recopiladas del Archivo de la Diputación Provincial de Sevilla y fuentes secundarias de diferentes repositorios para su interpretación. El resultado de la investigación reveló que el hospital de las Cinco Llagas de Sevilla fue una institución que exigió disciplina, fidelidad  y entrega a sus trabajadores, recibiendo en compensación salarios, manutención, alojamiento, ayudas de costa y retiro con ayuda monetaria y asistencial. La conclusión nos permite conocer a nivel micro la asistencia a trabajadores ancianos de un hospital  que llevaron una vida dedicada a la labor hospitalaria y que fueron merecedores de tal reconocimiento. Incluso, la sobrevivencia de esta práctica fue impulsada por sus mismos trabajadores entregando todo o parte de sus ingresos a los “jubilados” con la promesa de heredar aquellos cargos a modo de titularidad y de ser tratados de la misma forma al llegar a la senectud. Actitud que era valorado por los patronos de la institución como un signo de compromiso, fidelidad y confraternidad entre sus miembros. Esta ayuda asistencial fue una práctica llevada a cabo en algunas instituciones laicas y religiosas en España y replicada en las colonias españolas en América, como en Lima, capital de virreinato del Perú.

Marco conceptual asociado a la identidad e imagen profesional de enfermería en Chile

Introducción: La identidad e imagen de las enfermeras son conceptos interrelacionados que reflejan el sentido de uno mismo y las percepciones sociales sobre la profesión. Ambos son esenciales para el desarrollo de una práctica confiada y respetada. Objetivo: Develar el marco conceptual asociado a la imagen e identidad profesional de enfermería desde la perspectiva de enfermeras jubiladas. Materiales y Métodos: Estudio cualitativo basado en el paradigma constructivista y Teoría Fundamentada según Morse, que explora la identidad e imagen profesional de enfermería en Chile mediante entrevistas y grupos focales con enfermeras jubiladas. Para el análisis de los datos, se siguió la metodología propuesta por Charmaz. Sobre el rigor ético del estudio, se contó con la evaluación y aprobación de un Comité de Ética Científica independiente. Resultados: Participaron de este estudio 20 enfermeras jubiladas con una edad promedio de 74 años. Se establecieron 4 categorías que construyen la imagen social de las enfermeras y 3 categorías que construyen su identidad profesional. Discusión: Este estudio explora la imagen e identidad profesional de las enfermeras jubiladas, destacando cómo la pandemia mejoró la percepción pública de la profesión, de acuerdo con estudios internacionales. Han disminuido estereotipos como la feminización de la enfermería y su subordinación a la medicina, ampliamente descritos en la literatura. Las participantes se ven como líderes naturales, pero señalan deshumanización debido al agotamiento, tareas administrativas y los avances tecnológicos. Conclusiones: Resaltar una imagen auténtica y una identidad profesional coherente de la profesión fortalece su valor, estatus y reconocimiento social, lo que, a su vez, impacta positivamente en la calidad de los cuidados prestados a los pacientes.

Misinformation on cardiovascular disease spreads through social networks: a scoping review protocol

Por: Bhandari · B. · Zafra-Tanaka · J. H. · Mahapatra · P. · Njelekela · M. · Infante-Garcia · M. M. · Ramalingam · S. · Gonzalez-Rivas · J. P.
Introduction

Misinformation about cardiovascular health has the potential to negatively impact public health outcomes. Understanding the nature and spread of such misinformation is crucial for developing effective interventions to mitigate this potential risk. However, despite the critical importance of this issue, there is a gap in comprehensive reviews mapping the existing literature on cardiovascular health misinformation. This scoping review aims to map the existing literature on cardiovascular health misinformation, identifying its spread, prevalence, impact and strategies for correction across diverse populations and settings.

Methods

This review will follow the Joanna Briggs Institute guidelines for conducting a scoping review. A comprehensive search will be conducted across multiple databases, including MEDLINE, EMBASE, SCOPUS and Web of Science, along with grey literature sources. The last date of search was January 2025. The review will include studies without date that involve individuals affected by cardiovascular disease (CVD) misinformation, examine the spread, prevalence, impact or correction of misinformation related to cardiovascular health, and capture various cultural, geographic or setting-specific factors. The exclusion criteria include studies that do not directly address misinformation related to CVD. All identified records will be imported into Covidence systematic review software. Two reviewers will independently screen titles and abstracts, followed by full-text reviews of potentially relevant studies. Discrepancies will be resolved through discussion or by consulting a third reviewer. Data extraction will be conducted by two reviewers using a pre-piloted tool, and a descriptive presentation of the findings will be done. Both inductive and deductive content analysis methods will be employed for objectives related to the impact and strategies to combat misinformation.

Ethics and dissemination

Given that the study involves synthesising data from existing published literature, ethical approval is not required. The findings will be disseminated through international conference presentations, published in a peer-reviewed journal and shared with public health organisations and policymakers.

Factores de riesgo para la sobrecarga en cuidadores informales de personas mayores con demencia: una revisión rápida de las últimas evidencias

Introducción. El número de personas mayores está incrementando y esto lleva consigo un aumento de enfermedades relacionadas con la edad avanzada como la demencia. Se caracteriza por la pérdida de memoria u otras funciones mentales, que incapacita a los pacientes y precisan cuidados de otras personas, los cuidadores informales. El objetivo de esta revisión fue analizar los factores de riesgo que contribuyen a la sobrecarga en los cuidadores informales de personas mayores con demencia. Metodología. Se realizó una revisión rápida con metodología sistemática, en MEDLINE (PubMed), creando una estrategia de búsqueda (términos MeSH, palabras clave y los operadores booleanos). Resultados. Un total de 16 artículos fueron incluidos con diferentes metodologías. De todos ellos, se obtuvieron datos acerca del grado de demencia del anciano, el perfil y la carga del cuidador mediante la escala Zarit Burden Interview y factores que afectan a padecer mayor sobrecarga. Se comprobó que la mayoría de los cuidadores son mujeres de mediana edad y que conviven con el paciente sin importar el lugar de procedencia. Se expresa mayor sobrecarga sobre los cuidadores de pacientes con demencia que con aquellos pacientes sin ella. Discusión. Los cuidadores con mayor estrés y ansiedad, y cuyo grado de conocimientos acerca de la enfermedad es inferior a la media tienen una peor puntuación en la escala Zarit Burden Interview. Se debe prestar atención a los factores de riesgo para evitar situaciones de sobrecarga, siendo necesario el apoyo social, económico, emocional y familiar.

ABSTRACT

Introduction. The number of elderly people is increasing, and this brings with it an increase in age-related diseases such as dementia. It is characterized by the loss of memory or other mental functions, which incapacitates patients and requires care from other people, the informal caregivers. The objective of this review was to analyse the risk factors that contribute to burden in informal caregivers of elderly patients with dementia. Methodology. A rapid review with systematic methodology was performed in the MEDLINE (PubMed), developing a search strategy (MeSH terms, keywords, and Boolean operators). Results. A total of 16 articles were included with different methodologies. Data were obtained about the degree of dementia in the elderly, caregiver profile and burden using the Zarit Burden Interview scale, and factors that affect suffering greater burden. It was observed that most of the caregivers are middle-aged women and that they cohabit with the elderly without consideration of the place of origin of the patient. Caregivers of patients with dementia are more burdened than caregivers of patients without dementia. Discussion. Caregivers with greater levels of stress and anxiety and lower than median knowledge of the disease scored worse on the Zarit Burden Interview scale. Attention should be focused on risk factors to avoid overload, and social, economic, emotional, and family support is also necessary.

Complicaciones maternas en el embarazo adolescente: un estudio de revisión

Objetivo: Identificar las complicaciones maternas en el embarazo adolescente desde el contexto mundial. Método. Se siguió el protocolo de las guías (PRISMA ScR) y los manuales (JBI), utilizando los Descriptores en Ciencias de la Salud y el ordenador booleano AND: Complicaciones del embarazo AND adolescentes y palabras de texto libre, mismas que fueron insertadas en las bases de datos Dialnet, Pubmed, LILACS y SciELO, considerando los estudios primarios de textos completos que hayan investigado las complicaciones maternas en el embarazo adolescente, cuya metodología empleada haya sido de tipo descriptivo (transversal), incluyendo investigaciones retrospectivas o prospectivas, con una antigüedad no mayor a 10 años y adaptadas al idioma español, inglés o portugués. Resultados. Se encontró un total de 548 estudios primarios, los cuales fueron seleccionados de acuerdo a los criterios de elegibilidad, además de excluir los estudios duplicados en las bases de datos. El total de artículos primarios seleccionados para la revisión fue de 11 estudios en donde se identificaron como principales complicaciones maternas: trastornos hipertensivos, anemia, infecciones del tracto urinario, aborto, ruptura prematura de membranas, y hemorragias ante parto o postparto. Conclusión. La gestación en la adolescencia predispone al desarrollo de complicaciones maternas y en mayor proporción a la aparición de trastornos hipertensivos aumentando el riesgo de morbi-mortalidad materna y neonatal.

ABSTRACT

Objective. To identify maternal complications in adolescent pregnancy from the global context. Methodology. The protocol of the guidelines (PRISMA ScR) and manuals (JBI) was followed, using the Descriptors in Health Sciences and the Boolean computer AND: Complications of pregnancy AND adolescents and free text words, which were inserted in the Dialnet, Pubmed, LILACS and SciELO databases, considering the primary studies of full texts that have investigated maternal complications in adolescent pregnancy, whose methodology used was descriptive (cross-sectional), including retrospective or prospective research, no older than 10 years and adapted to Spanish, English or Portuguese language.Results. A total of 548 primary studies were found, which were selected according to the eligibility criteria, in addition to excluding duplicate studies in the databases. The total number of primary articles selected for the review was 11 studies where the main maternal complications were identified as: hypertensive disorders, anemia, urinary tract infections, abortion, premature rupture of membranes, and antepartum or postpartum hemorrhage. Disicussion. Adolescent gestation predisposes to the development of maternal complications and, to a greater extent, to the appearance of hypertensive disorders, increasing the risk of maternal and neonatal morbidity and mortality.

La labor del Protomedicato en la salud pública en el virreinato del Perú

El objetivo de la presente investigación es conocer el papel que cumplió el Protomedicato en la salud publica en el virreinato del Perú. La metodología utilizada fue la narración histórica siguiendo el método heurístico y hermenéutico, utilizando fuentes primarias documentales de archivos históricos peruanos y españoles. El resultado obtenido fue confirmar que el Protomedicato veló por la salud de los vecinos y que tenía carácter administrativo judicial y sus funciones principales fueron regularizar la labor de los que ejercieran cualquier tipo de atención sanitaria, otorgando licencias, fijando aranceles y vigilando el trabajo realizado en las boticas y la calidad de los medicamentos, a través de visitas periódicas. La conclusión determina que hubo mejoras sanitarias como consecuencia de la gestión del Protomedicato en el virreinato del Perú, proponiendo medidas salubres e, incluso, disponía la movilización de personal médico a través del virreinato y participaba ante cualquier consulta de otras entidades coloniales, como el cabildo, referentes a salud pública, como eliminación de acequias, declaración de pestes, y otros.

Attitude of Indian nurses towards importance of families in nursing care: A cross‐sectional study

Abstract

Aims and Objective

To evaluate the attitudes of Indian nurses towards the importance of family involvement in nursing care and the association between nurse attitudes and sociodemographic characteristics.

Background

Involving the family in the care process is crucial for delivering family- and patient-centred care and ensuring the best possible patient outcomes. Nevertheless, published literature revealed that the nurses may lack clarity regarding the role of family members in the patient's care, which in turn hinders families' participation in care.

Design

Cross-sectional descriptive study. The STROBE checklist was used to report the present study.

Methods

A total of 203 Nurses participated in a prospective cross-sectional study between May 2022 and August 2022. They were recruited through convenience sampling from two tertiary care centres in India. A two-part questionnaire was used to gather the data; the first section contained questions for gathering sociodemographic information, and the second part contained the standardized FINC-NA scale.

Results

The mean age of the nurses was (28.08 ± 4.722) years, and their median professional experience was 2.5 (1–5.5) years. Nurses' attitude regarding family's importance in patient care was found to be significantly associated (p ≤ .05) with education level, marital status, religion and hometown region.

Conclusion

In several items Indian nurses have positive attitudes towards family involvement in care but some of the lower scoring items can present opportunities for focused improvement. Continuing development programmes about family-centered care can constitute important strategies to improve the positive attitudes of nurses towards families in practice.

Patient and public contribution

No patient or public contribution.

Satisfacción usuaria en psiquiatría: niveles y factores asociados

Objetivo principal: Determinar los niveles de satisfacción usuaria y sus factores asociados, en una unidad hospitalaria psiquiátrica en Chile. Metodología: Participaron 479 personas, con un promedio de 37,5 años (44,9% mujeres). Se utilizó estadística descriptiva y un modelo de regresión lineal múltiple. Resultados principales: El promedio de satisfacción usuaria fue de 6,53 (rango 1 a 7). Se determinó que los factores asociados fueron la información entregada al paciente (p = 0,003), el acceso telefónico con familiares (p = 0,016), el uso del tiempo libre en la unidad (p < 0,001), la atención del personal de enfermería (p = 0,001), técnicos paramédicos (p = 0,003) y del personal médico (p = 0,01). Dentro de la infraestructura, solo la valoración de espacios comunes de la unidad fue significativa (p = 0,049). Conclusión principal: El nivel de satisfacción fue alto y sus factores se relacionan principalmente con la gestión del cuidado de enfermería.

Experiencia de estudiantes universitarios de salud al publicar en una revista académica de pregrado

Objetivo principal: Conocer la experiencia de estudiantes de carreras de la salud al publicar un artículo en una revista académica de pregrado, creada en el marco de los proyectos de innovación de una universidad chilena. Metodología: Investigación de diseño mixto, en la que se utilizó un cuestionario electrónico con preguntas abiertas, de selección y tipo Likert, previa firma de consentimiento informado. Se evaluaron las variables descritas como el proceso de publicación, las instrucciones a los autores, la comunicación con el equipo editor, la satisfacción con la publicación y el acceso electrónico a la revista. El cuestionario cualitativo contempló las dimensiones razones de publicar y aportes a los valores y competencias de la universidad. Se realizó análisis cuantitativo y análisis de contenido con enfoque cualitativo de una muestra de 54 estudiantes. Resultados principales: La comunicación con el equipo editor obtuvo la más alta calificación (83,33%). La calificación más baja (37%) fue obtenida en el acceso al número completo de la revista ya publicado. Los estudiantes reportaron que se fortaleció el valor de la “responsabilidad” y la competencia “visión analítica” luego de publicar. Conclusión principal: La experiencia de publicar fue muy bien evaluada por los estudiantes. La motivación de publicar fortalece competencias y valores y se consolida como una experiencia positiva. Los estudiantes se sienten parte de una comunidad del conocimiento colaborativa entre pares. Se debe mejorar algunos procesos editoriales que fortalezcan la comunicación con los estudiantes que son autores.

Utilidad de la técnica de canalización venosa bajo control ecográfico

Objetivo principal: Con este trabajo nos marcamos el objetivo de evaluar la utilidad del uso de la técnica de canalización de la vía venosa bajo con-trol ecográfico en aquellos pacientes que fracasó la técnica habitual de canalización periférica y analizamos las causas que determinaron el motivo del fracaso. Metodología: Realizamos un estudio prospectivo, observacional y descriptivo donde se analizaron las variables que presentaban los casos del estudio y las variables de la técnica de punción venosa ecográfica; obesidad, fragilidad capilar, adicción a drogas, tratamiento de larga duración asociado, punciones fallidas, localización venosa, calibre del catéter, tiempo empleado, escala analógica visual del dolor (E.V.A.) y éxito/fracaso en la punción venosa bajo ecografía. Resultados principales: La tasa de canalización resultó del 86.5% con un porcentaje de intentos a la 1ª, del 78,4% y a la 2ª del 21,6%. Se canalizó la V. Basílica en un 64,9%, con catéteres de 18G en un 81,1%, empleando entre 1 y 3 minutos en el 62,1%, con una E.V.A. ≤3 puntos en el 75,6% de los casos. La obesidad en el 29,7% y la fragilidad de los vasos en el 56,8% de los pacientes dificultó el acceso normal a la vía periférica y fue un factor que llevó a utilizar de modo preferente la ecografía. Conclusión principal: La ecografía es una técnica útil, reproducible y exitosa en pacientes con dificultades de acceso venoso resultando especialmente valiosa en enfermos obesos y con fragilidad de vasos. Debemos ampliar la muestra a toda la población para estudiar si estas dos características son determinantes a la hora de canalizar la vía venosa.

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