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Ayer — Junio 14th 2026Tus fuentes RSS

Global prevalence and determinants of hospital-acquired COVID-19: protocol for a systematic review and meta-analysis

Por: Ribaric · N. L. · ONeill-Byrne · Z. · Hellinger · A. · Pan · D. · Wilson · N. M. · Viola · I. M. · Walsh · T. S. · Lawton · T. · Afanasjevs · S. · Calabria · C. · De Angelis · F. · Brehm · T. T. · Zapf · A.
Introduction

A proportion of patients hospitalised for COVID-19 acquire the disease during their hospital stay, underscoring the risk of hospital-acquired COVID-19 (HA-COVID-19). This risk is presumed to be high, given how commonly and intensely air and surfaces within hospitals are reportedly contaminated with SARS-CoV-2. However, the true extent of HA-COVID-19 worldwide remains unknown, with limited understanding of factors that influence its occurrence and how these have evolved over time. This review will therefore aim to estimate the pooled prevalence of HA-COVID-19 among hospitalised COVID-19 patients globally and investigate differences by country, type of hospitals, medical specialty, length and timing of studied periods.

Methods and analysis

A systematic review and meta-analysis will be conducted adhering to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. MEDLINE and PubMed Central (via PubMed), Scopus, Embase (via Ovid), the Web of Science Core Collection as well as websites of public health agencies (PHA) will be searched until 1 July 2026. All journal articles and sources from PHAs reporting any primary data on the prevalence of HA-COVID-19 will be included. Methodological quality will be assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Studies Reporting Prevalence Data. The primary outcome will be the global prevalence of HA-COVID-19. Data synthesis will include random-effects proportional meta-analysis. Estimates will be presented with two-sided 95% CIs and heterogeneity assessed using the I² statistic.

Ethics and dissemination

Ethical approval is not needed as no original data will be generated. This review will be published in an international, peer-reviewed journal.

PROSPERO registration number

CRD420251136884.

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Health Outcomes Led by Advanced Practice Nurses in Patients With Chronic Wounds: A Scoping Review

ABSTRACT

Aim

To examine and map the available literature on outcomes associated with interventions carried out by advanced practice nurses in chronic wound care.

Background

The role of the advanced practice nurses in wound care is identified as a key element in the management of patients with chronic wounds. However, the literature offers fragmented knowledge of the outcomes associated with their practice.

Design

Scoping review.

Methods

This scoping review was conducted following the methodological framework proposed by Arskey and O'Malley, following the Preferred Reporting Item for Systematic Review and Meta-analysis for Scoping Review. PRISMA-ScR Checklist is included in the manuscript. Observational or experimental studies related to patients affected by chronic wounds and cared for by advanced practice nurses in wound care were included.

Data Sources

The following databases were queried: PubMed, CINAHL, Cochrane Library, and Scopus from 01 May 2025 to 31 October 2025.

Results

The search strategy in the consulted databases identified 1956 studies; 31 met the inclusion criteria. Different types of chronic wounds were investigated: diabetic foot ulcers, venous leg ulcers, and pressure injuries. The most frequently measured outcomes were clinical responses (healing, recurrence, complications), organizational efficiency (referrals, resource utilization), and patient-reported outcomes.

Conclusion

Evidence from the included studies suggests that Advanced practice nurses led wound care models may be associated with faster healing, lower recurrence and complication rates, and more efficient care pathways, across different settings. This review highlights the global applicability of APN-led models, showing consistent improvements in clinical, organizational, and patient-reported outcomes through core interventions.

Reporting Method

This scoping review follows Arskey and O'Malley's methodological framework and the Preferred Reporting Item for Systematic Review and Meta-analysis for Scoping Review.

Patient or Public Contribution

No Patient or Public Contribution.

Protocol Registration

The revision protocol was registered on the OSF (https://doi.org/10.17605/OSF.IO/P9TA4).

Implementing Wound Hygiene in the Italian Healthcare Context: Expert Recommendations for the Management of Venous Leg Ulcers

ABSTRACT

The ‘Wound Hygiene Italia’ project was designed to provide expert-driven recommendations for the assessment, management and monitoring of venous leg ulcers, tailored to diverse settings of care (hospital, ambulatory and home care). The recommendations, developed by a multidisciplinary panel, emphasise the implementation of the Wound Hygiene strategy, a systematic approach targeting biofilm as a primary barrier to wound healing. Wound management is structured around four steps: cleansing, debridement, edge refashioning and dressing selection adapted to the wound bed characteristics, care setting and clinical capabilities, embedded in a holistic approach through comprehensive patient assessment and monitoring of overall well-being. The findings highlight the necessity of interdisciplinary collaboration, standardised tools and continuous patient monitoring, as assessed by objective metrics, such as wound size measurements and photographic documentation. Effective communication with patients and caregivers is also essential to ensure treatment adherence and foster trust in the care process. This framework integrates evidence-based practices to optimise outcomes and patient quality of life. By addressing both clinical and psychosocial factors, the recommendations promote a holistic, patient-centred approach that underscores the importance of education, structured follow-ups and tailored interventions.

<i>In vivo</i> and <i>in vitro</i> susceptibility and inflammatory response of postnatal mouse cortical neurons and glial cells to zika virus infection

by María-Angélica Calderón-Peláez, Myriam L. Velandia-Romero, Jaime E. Castellanos

Zika virus (ZIKV) poses a significant threat to neural tissue, causing substantial damage to unborn children exposed to the virus in utero, with consequences that can manifest even after birth, despite being born with a normal head circumference. Regardless of the extensive research, the interactions between ZIKV and the nervous system cells remain insufficiently understood, particularly regarding how neuronal responses influence broader inflammatory and viral dynamics especially in postnatal stages of development. This study evaluated the susceptibility to ZIKV infection, viral replication, immune response, and survival of neurons, astrocytes and microglial cells during postnatal developmental stages, using both in vivo and in vitro mice models. In vivo, a non-lethal but extensive infection of neurons and microglia was shown. The infection caused a robust but controlled immune response with elevated levels of MCP-1, TNF-α, and IL-6, that prevented severe neuronal damage. In vitro, neurons exhibited high susceptibility to ZIKV, with elevated levels of pro-inflammatory cytokines and IFN-β, indicating a strong inflammatory response. In contrast, astrocytes and microglia displayed varied responses, contributing to a pro-inflammatory feedback loop. These findings offer critical insights into the cellular dynamics of ZIKV infection, enhancing our understanding of its effects during postnatal nervous system development. By clarifying the interactions between ZIKV and neuronal cell types, this study deepens the comprehension of the virus’s pathophysiology and its broader implications for neurodevelopmental outcomes, extending beyond the well-documented association with microcephaly.

Temperature-dependence of early development of zebrafish and the consequences for laboratory use and animal welfare

by Angelina Miller, Katja Lisa Schröder, Karsten Eike Braun, Caitlin Steindorf, Richard Ottermanns, Martina Roß-Nickoll, Henner Hollert, Thomas Backhaus

Zebrafish (Danio rerio) are widely used in biological research, but the impact of incubation temperatures on developmental endpoints is still insufficiently studied. This study quantifies developmental differences in zebrafish embryos incubated at 26°C and 28°C, focusing on key endpoints (heartbeat onset, hatching time, eye size, yolk sac consumption, and body length). For this purpose, we recorded a high-resolution time series comprising hourly observations of early developmental stages and key events and bi-hourly observations of body length until 120 hours post fertilization. Additionally, we recorded a low-resolution time series at 72, 96, and 119 hours post fertilization for detailed measurements of eye size, yolk sac area, and body length. Embryos incubated at 26°C showed consistent delays in developmental stages compared to those at 28°C, with delays becoming more pronounced at later stages. Yolk sac consumption was delayed by about 19.8 hours at 26°C by 119 hours post fertilization, suggesting a delayed onset of independent feeding. These findings suggest that time-based regulatory limits for rearing zebrafish, such as the 120-hour threshold in German regulations (TierSchVerV), do not fully account for temperature-dependent development. The results emphasize the need for guidelines linking incubation temperatures to developmental progress.

Evaluating AI-based comprehensive clinical decision support for sepsis and ARDS: protocol for a Clinician Turing Test

Por: Angeli Gazola · A. · Bishop · N. S. · Schmid · B. E. · Pirracchio · R. · Valley · T. S. · Bhavani · S. V. · Krutsinger · D. C. · Giannini · H. M. · Lu · Y. · Ungar · L. H. · Meyer · N. J. · Kerlin · M. P. · Weissman · G. E.
Introduction

Few artificial intelligence (AI) clinical decision support systems (CDSSs) are ever evaluated in practice. Although some signal of clinical effectiveness may be needed to justify AI deployment and testing, such data are typically unavailable in early-stage research. This conundrum is especially relevant in the intensive care unit (ICU), where conditions like sepsis and acute respiratory distress syndrome (ARDS) require high-stakes decisions. Our group developed the AI ventilator assistant (AVA), a novel AI CDSS for patients with sepsis ARDS receiving invasive mechanical ventilation. But the promising results of predictive performance estimates are not sufficient to assess AVA’s clinical safety and appropriateness prior to future evaluation and deployment. Therefore, we propose a Clinician Turing Test as a novel validation approach to determine whether clinicians can distinguish AVA-generated treatment recommendations from those enacted by real human clinicians. If AVA’s recommendations are consistently indistinguishable from those of real clinicians, thereby ‘passing’ this Turing test, this would provide a strong preclinical signal of safety and appropriateness.

Methods and analysis

This multisite, randomised, electronic, vignette-based Phase 1b study will use a Clinician Turing Test design. We aim to recruit 350 critical care clinicians, including physicians and advanced practice providers from six US hospitals. Participants will review nine clinical vignettes of patients with sepsis and ARDS derived from the Molecular Epidemiology of Severe Sepsis in the ICU cohort and an associated profile of a suggested treatment plan. For each participant–vignette combination, the source of the treatment profile will be randomly assigned (AI-generated by AVA vs the actually enacted treatment from real human clinicians) in a 1:1 allocation. The primary endpoint is the participants’ accuracy in identifying whether a treatment profile was AI-generated or human-generated, assessed using equivalence testing through a mixed-effects logistic regression model with random effects for participants and vignettes. Secondarily, a fitted binary classifier will assess discrimination ability using the C-statistic. Secondary endpoints include clinicians’ perceptions of the safety and appropriateness of the treatment profiles, confidence in distinguishing AI-generated and human-generated recommendations, interest in AI CDSSs for sepsis and ventilator management and the time to complete the survey. This novel Phase 1b design provides preliminary but essential information about an AI CDSS’s clinical appropriateness without the risk or cost of actual deployment, thereby informing decisions about future clinical implementation and evaluation in real clinical environments.

Ethics and dissemination

This protocol was approved by the Institutional Review Board of the University of Pennsylvania (Protocol #858201). Results are expected in 2026 and will be submitted for publication in peer-reviewed journals and presented at scientific conferences.

Trial registration number

NCT07025096.

Experiences and impact of chronic pain in South Africans living in a rural area: a qualitative study

Por: Mulaudzi · M. · Ratshinanga · A. · Mohale · J. · Ramoshai · T. · Evangeli · M. · Pincus · T. · Parker · R. · Umunnakwe · C. N. · Tempelman · H. · Wadley · A.
Objectives

Previous work in South Africans living with HIV and chronic pain has raised questions regarding maintained levels of physical activity while in pain, patterns of pain disclosure and recruitment of social support. Recent data suggest that pain in people living with HIV may be more due to issues of poverty rather than HIV. We explored how South Africans with chronic pain living in a rural area: (1) understand and experience chronic pain, (2) how chronic pain affects activity levels and (3) the relationship between pain disclosure and social support.

Design

We conducted a qualitative study using in-depth interviews. Transcripts were analysed using thematic data analysis.

Setting

The Ndlovu Care Group Research Centre in the rural Elandsdoorn, Dennilton area in Limpopo province, South Africa, between April and July 2019.

Participants

34 individuals (19 women, 15 men) with a mean age of 37 years (SD 8) living with chronic pain, half of whom were living with HIV, and half without.

Results

Perceived causes of pain included illness or injury, ‘thinking too much’ and non-Western perspectives. Three patterns of activity in response to chronic pain emerged: perseverance, reduced activity and complete inactivity. Reasons for perseverance included fear of losing income, perceived social stigma or no social support. Patterns of pain disclosure included full, selective (telling some people but not others depending on their perceived trustworthiness), partial (sharing pain presence but not how severe it was) and non-disclosure. Disclosing pain was common in women and was used to recruit practical support. Men rarely disclosed to recruit support, and if they did, would recruit for financial support. Disclosing pain was also a strategy to avoid the social stigma of being labelled ‘lazy’. Patterns of activity, disclosure and type of support recruited did not differ between those with and without HIV.

Conclusions

Our findings suggest that activity levels, disclosure and recruitment of support in South Africans living with chronic pain are influenced by low income, social stigma and gender, rather than HIV.

<i>Mycobacterium tuberculosis</i> complex lineages and drug resistance patterns among tuberculosis patients with or without diabetes mellitus in southern Ghana

by Emelia Konadu Danso, Prince Asare, Amanda Yaa Tetteh, Phillip Tetteh, Augustine Asare Boadu, Ivy Naa Koshie Lamptey, Augustina Angelina Sylverken, Kwasi Obiri-Danso, Jane Sandra Afriyie-Mensah, Abraham Adjei, Dorothy Yeboah-Manu

Drug-resistant (DR) tuberculosis (TB) and diabetes mellitus (DM) are intersecting epidemics that complicate management of both diseases and worsen patient outcomes. We conducted a prospective cohort study of 758 GeneXpert-confirmed pulmonary TB patients, of whom 75 had DM. Demographic, clinical, radiographic, and anthropometric data were collected at baseline. Sputum samples were cultured for mycobacterial isolation, and the obtained isolates were characterized for Mycobacterium tuberculosis complex (MTBC) lineage and drug-susceptibility testing using spoligotyping and microplate alamar blue assay. The TB-diabetes (TB-DM) comorbid cohort was older [TB-DM: 53/75 (70.7%) vs. 241/683 (35.3%) aged 41–60 years) (p 

Do professional experience and qualification influence knowledge about law concerning informed consent and end-of-life decisions? A quantitative online survey among German intensive care physicians

Por: Schumann · C. · Wachter · M. · Eslauer · E. · Angeli · R. · Girrbach · F. · Weiss · M. · Friedrich · S. · Simon · P. · Heller · A. R.
Background

Recently, legal questions have increasingly arisen in intensive care medicine (ICM), especially when it comes to end-of-life decisions. Still, for Europe, there is not much evidence about doctors’ situational legal knowledge and legal education during medical studies and further qualification. The present study was initiated to analyse these hitherto unexplored aspects in Germany.

Design

A quantitative online survey has been performed among German intensive care physicians. The voluntary participants of the anonymous online survey were asked to answer legal questions related to end-of-life policies, informed consent, surrogate decision making or advance directives. We tested pure factual knowledge in five questions. The other five questions tested situational knowledge using case vignettes. Every question could be answered with ‘yes’, ‘no’ or ‘do not know’. Furthermore, the participants were asked to assess their subjective certainty on a Likert scale and to provide information about their professional experience (PE) and qualification.

Setting

All members of the two German professional societies for anaesthesiology who work in ICM were asked to take part in the survey.

Participants

952 completed questionnaires were analysed. 86% of the participants were specialists, and 56% held the additional qualification in ICM. 78% had more than 10 years of general clinical experience, and 62% had more than 5 years of experience in ICM.

Results

On average, the participants answered the five facts–questions in 90.8% correctly. However, only 73.6% of the five case vignettes were answered correctly. Specialists, physicians with a lot of PE or physicians holding the additional qualification in ICM did not perform better than assistants or physicians with little PE.

Conclusion

German intensive care physicians have relevant gaps regarding situational legal knowledge, which are independent of their PE or qualification and persist. This may be due to difficulties in interpretation and implementation of law. Since these knowledge gaps can lead to liability and criminal prosecution, these gaps should be closed through awareness-raising and continuous education.

Integrated analysis of genome, metabolome, and transcriptome reveals a bHLH transcription factor potentially regulating the accumulation of flavonoids involved in carrot resistance to Alternaria leaf blight

by Claude Emmanuel Koutouan, Marie Louisa Ramaroson, Angelina El Ghaziri, Laurent Ogé, Abdelhamid Kebieche, Raymonde Baltenweck, Patricia Claudel, Philippe Hugueney, Anita Suel, Sébastien Huet, Linda Voisine, Mathilde Briard, Jean Jacques Helesbeux, Latifa Hamama, Valérie Le Clerc, Emmanuel Geoffriau

Resistance of carrot to Alternaria leaf blight (ALB) caused by Alternaria dauci is a complex and quantitative trait. Numerous QTL for resistance (rQTLs) to ALB have been identified but the underlying mechanisms remain largely unknown. Some rQTLs have been recently proposed to be linked to the flavonoid content of carrot leaves. In this study, we performed a metabolic QTL analysis and shed light on the potential mechanisms underlying the most significant rQTL, located on carrot chromosome 6 and accounting for a large proportion of the resistance variation. The flavonoids apigenin 7-O-rutinoside, chrysoeriol 7-O-rutinoside and luteolin 7-O-rutinoside were identified as strongly correlated with resistance. The combination of genetic, metabolomic and transcriptomic approaches led to the identification of a gene encoding a bHLH162-like transcription factor, which may be responsible for the accumulation of these rutinosylated flavonoids. Transgenic expression of this bHLH transcription factor led to an over-accumulation of flavonoids in carrot calli, together with significant increase in the antifungal properties of the corresponding calli extracts. Altogether, the bHLH162-like transcription factor identified in this work is a strong candidate for explaining the flavonoid-based resistance to ALB in carrot.

Development and Evaluation of Precision Health Competencies

ABSTRACT

Aim

To develop precision health (PH) competencies and evaluate their comprehensiveness and fit into nursing practice.

Design

A modified e-Delphi technique was used to gather perceptions and achieve consensus on the inaugural set of PH domains, competency statements and sub-competencies developed by a workgroup formed under the aegis of the American Nurses Association (ANA).

Methods

A set of PH competencies and sub-competencies was developed by the ANA workgroup, beginning with a literature review, followed by a multi-step work process of the group over 3 years (2022–2025). Then, a modified e-Delphi technique was conducted via a four-point Likert scale Qualtrics survey, using a purposive sample of PH experts. The respondents were asked to agree or disagree with each competency or sub-competency statement and suggest modifications. The threshold of concordance was set at 80%.

Results

The ANA workgroup reached consensus on six domains, six competency statements and 43 sub-competency statements to represent PH in nursing practice in its entirety. Forty experts in the field evaluated and offered revisions to the final 44 sub-competencies that represent the knowledge and skills necessary for PH in general nursing practice. A majority of the competency statements obtained favourable agreement from the expert panel, and a typical pattern of convergence was observed over two rounds of evaluation.

Conclusions

The development of PH competencies is the essential first step in the attempt to integrate PH into nursing practice.

Implications

The competency statements will inform nursing curricula, clinical practice guidelines, funding opportunities and role expectations in all healthcare settings.

Impact

This work sets the stage for subsequent interprofessional practice initiatives and research exploring how these competencies influence patient outcomes, workforce readiness and the practical integration of advanced technologies into precise care.

On the Move to Surgery: A Scoping Review of Patient‐Reported Outcomes for Preoperative Walking Into the Operating Theatre

ABSTRACT

Introduction

Although healthcare infrastructure has improved in recent years, the preoperative journey of patients is often accompanied by anxiety. Allowing patients to walk to the operating theatre is a simple, yet underexplored strategy that may enhance their sense of autonomy and reduce anxiety. As patient-centred care gains importance, evaluating the effects of this approach on patient-reported outcomes may be more relevant than widely assumed.

Aim

In this scoping review, we aim to analyse the published literature on preoperative walking into the operating theatre and patient-reported outcomes, such as anxiety and satisfaction.

Design

This study was a scoping review that followed the Joanna Briggs Institute methodology and Preferred Reporting Items for Systematic Reviews and Meta-Analyses, Scoping Review extension guidelines.

Methods

Inclusion criteria were adult patients undergoing elective surgery and walking to the operating theatre. Data were extracted using a standardised form, and critical appraisal was performed by using ROBINS-I V2.0, RoB2 and ROB-E tools.

Data Sources

Embase, MEDLINE, Cochrane databases (OVID) and CINAHL (EBSCOhost) were searched up to 31st January 2025.

Results

Our search identified 958 articles, with seven trials included in the final analysis. The studies, published between 1994 and 2022, involved 3001 patients from North America, Asia and Europe. The interventions varied, but most patients reported improved satisfaction and reduced anxiety when walking to the operating theatre. No adverse events were reported, although patient preferences varied, with younger patients more likely to prefer walking.

Conclusion

Walking to the theatre positively impacts patient satisfaction and autonomy. However, patient selection is key, as not all individuals are physically or mentally prepared for walking. Future research could explore unaccompanied walking and its effects on hospital resource utilisation. Preoperative walking is a beneficial intervention that enhances patient satisfaction and reduces anxiety, providing a feasible alternative to bed transport for many elective surgical patients.

Patient or Public Contribution

No patient or public involvement.

Assessment of vestibulo-ocular reflex function in people with Parkinsons disease: a cross-sectional study in a rehabilitation setting using the video head impulse test

Por: Ferri · N. · Casagrande Conti · L. · Manzari · L. · Piatti · D. · De Angelis · D. · Nocentini · U. · Tramontano · M.
Background

Parkinson’s disease (PD) is a neurodegenerative, progressive disorder known for motor and non-motor symptoms. The vestibular system, via the vestibulo-ocular reflex (VOR), is crucial for maintaining dynamic gaze stability, and its role in PD is raising interest among researchers. Indeed, vestibular dysfunction in PD may exacerbate postural instability and gait disturbances; however, the prevalence of vestibular dysfunctions remains unclear. This study aims to objectively investigate the VOR function in people with PD using the video head impulse test.

Methods

This is a cross-sectional study conducted in a neurorehabilitation hospital. People with PD were included if they had no cognitive impairment and the ability to walk without physical assistance. The video head impulse test was used to assess the VOR function across all six semicircular canals, using both the Head Impulse Paradigm (HIMP) and the Suppression Head Impulse Paradigm (SHIMP) paradigms.

Results

35 people with PD (mean age: 69.9±8.4; 11 females) with moderate motor symptoms (MDS-UPDRS-part III: 27.7±6.8) were included. Using normative cut-offs, 69% of the participants had at least one dysfunctional canal (60% hypo-gain, 9% hyper-gain). The prevalence reached 83% when both the HIMP and SHIMP paradigms were considered.

Conclusion

There is a high prevalence of vestibular dysfunction in people with PD. The instrumental assessment of VOR gains could reveal undiagnosed vestibular dysfunctions and, in the future, lead to more specific rehabilitation management of people with PD.

Asociación entre factores motivacionales y desempeño laboral de profesional enfermero en dos hospitales de tercer y cuarto nivel de complejidad

Introducción: La motivación cumple un rol fundamental sobre todo en el desempeño laboral del profesional de Enfermería. Esta motivación representa un factor protector tanto para el profesional de Enfermería como también al paciente que se encuentra a su cuidado. Se objetivó analizar la relación existente entre factores motivacionales y desempeño laboral del profesional de Enfermería quienes ejercen funciones en dos hospitales del departamento Central 2023. Metodología. Estudio observacional descriptivo transversal realizado en dos centros asistenciales de referencia nacional, de alta complejidad de la República del Paraguay, muestreo no probabilístico por conveniencia. El instrumento, un cuestionario pre-elaborado y validado. Resultados. Respeto al desempeño laboral, predominó el nivel alto. En referencia a las dimensiones del desempeño laboral, ha predominado mayoritariamente el nivel alto, no registrándose ningún participante en el nivel bajo. Al relacionar los factores motivacionales con el desempeño laboral, se encontró asociación estadísticamente significativa, con lo que se acepta la hipótesis de investigación que indica que existe asociación entre factores motivacionales y el desempeño laboral de profesionales de enfermería. Discusión. Al relacionar los factores motivacionales con el desempeño laboral, se observó una asociación estadísticamente significativa. Esto se respalda en un estudio realizado en Perú, cuyos resultados sugieren que el desempeño laboral de los profesionales de enfermería estaría influenciado por la dependencia de factores motivacionales extrínsecos. Conclusión: Se recomienda fortalecer programas de reconocimiento y mejora de condiciones laborales para estimular la motivación extrínseca, como implementar oportunidades de desarrollo profesional y participación en la toma de decisiones.

ABSTRACT

Introduction: Motivation plays a fundamental role, especially in the work performance of nursing professionals. This motivation represents a protective factor for both the nursing professional and the patient under their care. The objective was to analyze the existing relationship between motivational factors and work performance of nursing professionals who work in two hospitals in the Central department 2023. Methodology. A cross-sectional, descriptive, observational study carried out in two national reference, highly complex healthcare centers in the Republic of Paraguay, using a non-probabilistic convenience sampling. The instrument was a pre-prepared and validated questionnaire. Results. Regarding work performance, a high level predominated. Regarding the dimensions of work performance, the high level predominated, with no participants registered at the low level. When relating motivational factors with work performance, a statistically significant association was found, thereby accepting the research hypothesis that indicates an association between motivational factors and the work performance of nursing professionals. Discussion. When relating motivational factors to job performance, a statistically significant association was observed. This is supported by a study conducted in Peru, whose results suggest that nursing professionals' job performance may be influenced by their dependence on extrinsic motivational factors. Conclusion. Strengthen recognition programs and improve working conditions is recommended to stimulate extrinsic motivation, such as implementing opportunities for professional development and participation in decision-making.

Prácticas culturales y ambientales del ámbito rural de Perú que influyen en la salud infantil

Introducción: Algunas prácticas ambientales arraigadas culturalmente ocasionan enfermedades infantiles como: diarreas, neumonías, dermatitis, lesiones domésticas no intencionales, etc. Objetivos: Describir las prácticas culturales y ambientales del ámbito rural de Perú que influyen en la salud infantil. Metodología: Investigación cualitativa, descriptiva, el escenario fueron los hogares de 15 madres de familia, residentes rurales de la costa norte de Perú; la muestra fue delimitada por saturación y redundancia, el muestreo no probabilístico por conveniencia. Los datos se recolectaron mediante entrevista semiestructurada y procesados según el análisis de contenido. Resultados: A) Riesgo en la salud infantil por práctica cultural y ambiental de cocina a fuego abierto, B) Práctica cultural y ambiental en la eliminación de excretas, C) Costumbre de quema de residuos sólidos. Conclusiones: La mayoría de las madres de la zona rural cocinan a fuego abierto, usan leña, esto es un riesgo para los niños que permanecen con ellas. Eliminan las excretas en pozos ciegos, debido a la falta de saneamiento. Además, manifiestan un inadecuado manejo de residuos sólidos, eliminados en espacios abiertos que favorecen la proliferación de vectores, para posteriormente ser quemados.

História da institucionalização do cuidado de enfermagem em psiquiatria em uma cidade do nordeste do Brasil

A assistência psiquiátrica brasileira começou nas Santas Casas de Misericórdia até o surgimento dos hospitais psiquiátricos. Os objetivos deste estudo foram identificar vestígios do cuidado de enfermagem em psiquiatria nas primeiras instituições criadas no estado do Piauí, região Nordeste do Brasil e analisar suas relações com a institucionalização deste grupo na primeira metade do
século XX. Trata-se de um estudo qualitativo, histórico social, com dados publicados na mídia jornalística, coletados em arquivos públicos brasileiros. A análise, sob o referencial teórico foucaultiano, seguiu a metodologia de triangulação das fontes e interpretação de dados. Resultados: duas instituições iniciaram a assistência psiquiátrica no estado: o Asylo de Alienados, instituição pública criada em 1907, e o Sanatório Meduna, instituição privada inaugurada em 1954. Apesar do intervalo de 47 anos entre tais instituições, ambas instituíram o modelo manicomial, cuja prática assistencial incluía longos períodos de internação e tratamento disciplinar. Tal modelo abriu o mercado de trabalho para a enfermagem em psiquiatria, que se constituiu inicialmente de pessoas sem preparo formal, devido a inexistência de cursos de enfermagem no estado. Conclusão: o cuidado de enfermagem em psiquiatria foi institucionalizado no
Piauí/Brasil de acordo com a psiquiatria tradicional e a ausência de um saber próprio da enfermagem a colocou em condições de submissão ao poder médico, com poucos avanços na primeira metade do século XX.

Vivencias del “YO PURO” en mujeres privadas de su libertad con antecedentes de consumo de drogas

Objetivo: describir las vivencias del “YO PURO” en mujeres privadas de libertad con antecedentes de consumo de drogas. Metodología: estudio cualitativo descriptivo de enfoque fenomenológico, utilizando un análisis de contenido temático e inductivo. La selección de participantes se realizó mediante un muestreo no probabilístico e intencional, incluyendo a seis mujeres privadas de su libertad. Para la recolección de datos, se aplicó una entrevista en profundidad basada en una pregunta detonadora. El análisis se llevó a cabo siguiendo los planteamientos propuestos por Edmund Husserl. Resultados: emergieron siete temas con sus unidades de significado. Experiencia en prisión, experiencia vivida del consumo de sustancias, dependencia y necesidad, reflexión y cuestionamiento del “YO PURO”, Sentimientos de culpa y pérdida, resignificación del presente a través de “YO PURO” y Anhelo de reconstrucción familiar. Conclusión: Este estudio exploró las vivencias de mujeres en reclusión, destacando los factores que influyen en su realidad diaria. Desde el enfoque fenomenológico de Edmund Husserl, se evidenció que la prisión no solo implica sufrimiento, sino que también propicia reflexión y transformación personal.

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