Evaluation of the impact of atherosclerotic cardiovascular disease (ASCVD), particularly polyvascular disease, on 30-day and 365-day mortality among intensive care unit (ICU) patients diagnosed with sepsis.
Retrospective cohort study.
This study was conducted using data from the Medical Information Mart for Intensive Care IV, a publicly available critical care database from a tertiary care hospital in the US.
A total of 7895 adult ICU patients with sepsis were included between 2008 and 2022. Among them, 3314 (41.97%) had ASCVD, defined by International Classification of Diseases (ICD) codes for coronary artery disease, peripheral artery disease or stroke.
The primary outcomes were all-cause mortality at 30 and 365 days following ICU admission.
ASCVD patients with a greater number of disease beds tend to be male, older, have lower body mass index, heart rates, mean blood pressure, respiratory rate and temperature, compared with non-ASCVD patients. Before propensity-score matching, patients with ASCVD (3314) had significantly higher 30-day (29.21% vs 24.14%, p
Integrated management of sepsis and ASCVD—using targeted interventions such as tailored pharmacotherapy and risk factor modification—may reduce mortality and morbidity in this high-risk population.
To investigate whether systemic lupus erythematosus (SLE) increases the risk of cataract development and to evaluate the impact of corticosteroid use and dosage on this risk.
Nationwide retrospective cohort study.
Using Taiwan’s National Health Insurance (NHI) database, which covers over 99.9% of the population.
The SLE cohort included 30 501 newly diagnosed adults from 2011 to 2020. For each patient with SLE, four individuals without SLE were selected from the NHI database using frequency matching by age (in 5 year intervals), gender and index year of diagnosis, resulting in a comparison cohort of 122 004 individuals.
The primary outcome was incident cataract. Secondary outcomes included risk stratification by age, sex, comorbidities and corticosteroid dose.
SLE patients had a higher incidence of cataracts than non-SLE individuals (adjusted HR (aHR) = 1.73, 95% CI 1.66 to 1.81). Stratified analyses showed elevated risks in women (aHR=1.74, 95% CI 1.66 to 1.83), men (aHR=1.68, 95% CI 1.52 to 1.86), and across age groups 20–49 years (aHR=2.32, 95% CI 2.11 to 2.56), 50–64 years (aHR=1.60, 95% CI 1.51 to 1.69), and ≥65 years (aHR=1.50, 95% CI 1.36 to 1.66). Analysis of corticosteroid exposure revealed that cumulative dose showed a trend towards increased risk at high exposure (adjusted OR (aOR) = 1.14, 95% CI 0.99 to 1.31), while average daily dose demonstrated a dose–response effect: 1–5 mg/day (aOR=1.31, 95% CI 1.13 to 1.52) and ≥5 mg/day (OR=2.48, 95% CI 2.16 to 2.86).
Adults with SLE have an increased risk of developing cataracts compared with matched controls, and higher average daily corticosteroid doses are associated with this risk. These findings highlight the need for careful monitoring of ocular complications in SLE patients.
The study aims to assess the associated influencing oncology nurses’ perceptions of managers’ empowering leadership style and to examine the influence of sex, work experience, shift work, membership of an oncology nursing association or a scientific society, nursing educational level and specialised nursing training in oncology on oncology nurses’ perceptions of managers’ empowering leadership style and its subdimensions.
Descriptive cross-sectional study.
In March 2024, oncology nurses employed in oncology settings were invited to participate.
All Italian oncology nurses who were currently employed were eligible to participate.
The Italian version of the Empowering Leadership Questionnaire was used to assess nurses’ perceptions of managers’ performance in leading by example, participative decision-making, coaching, informing and demonstrating concern/interacting with the team.
A total of 298 nurses agreed to participate. The associated factors for an empowered leadership style across all subdimensions were sex (p=0.006) and the educational level in nursing (p=0.004). Participative decision-making, coaching, informing and demonstrating concern/interacting with the team subdimensions were associated with shift work. Participation in scientific associations (p=0.005) was also influential.
Exploring the data according to the nursing specialisation appeared intriguing, since it could be a more indicative suggestion for future interventions to implement an empowering leadership style in clinical nursing practice and better inform health policymakers to achieve the right solution in their health organisations.
We aimed to understand the factors affecting psychological well-being of patients undergoing haemodialysis (HD). First, we explored how physical symptom severity, emotional distress and social support influence psychological well-being. Second, we examined the impact of different types of social support. Third, we investigated whether any variables mediate the relationship with psychological well-being.
A cross-sectional study, a type of observational design, was conducted on patients at a medical centre in Taiwan in 2020.
A total of 117 outpatients who had undergone regular HD for at least 3 months were enrolled.
The psychological well-being was assessed through self-report questionnaires.
We found that emotional distress (β=–0.25, p=0.033) had a significant negative impact on psychological well-being. However, the presence of appraisal support mitigated this effect. Specifically, appraisal support fully mediated the adverse impact of emotional distress on psychological well-being. In addition, the severity of physical symptoms was generally mild and did not influence psychological well-being.
Receiving appraisal support from family, friends and healthcare professionals not only alleviates emotional distress but also enhances psychological well-being both directly and indirectly among patients undergoing HD. Healthcare professionals should address issues of personal importance while serving as consultants, educators and evaluators to support patients in managing their chronic condition.
Hospital-based nurses and midwives play a pivotal role in promoting, protecting and supporting breastfeeding. However, variation in preservice education, in-service training and institutional policies contributes to inconsistent breastfeeding support across healthcare systems. Given the global push toward improving breastfeeding outcomes and the centrality of skilled nursing support, this scoping review protocol aims to systematically map the breadth, characteristics and reported outcomes of breastfeeding education and training initiatives targeting hospital-based nurses and midwives.
This scoping review will be conducted in accordance with the methodological framework developed by Arksey and O’Malley and advanced by the Joanna Briggs Institute (JBI). A systematic search will be conducted across major databases including OVID Medline, CINAHL, Scopus and Web of Science, as well as grey literature sources. Studies will be selected using the Population–Concept–Context (PCC) framework, focusing on breastfeeding-related education and training interventions designed for nurses and midwives in hospital settings. Two independent reviewers will screen all titles, abstracts and full texts, extract data using a standardised tool and resolve discrepancies via discussion or third-party consultation. The extracted data will be analysed using descriptive statistics and thematic synthesis to identify trends, gaps and directions for future research. The literature search will be conducted between August and October 2025.
This scoping review involves the analysis of existing literature and does not require ethical approval. The findings will be reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines. Results will be disseminated through peer-reviewed publication and presentations at nursing and maternal–child health conferences to inform educators, hospital administrators and policy makers involved in breastfeeding support and clinical education.