FreshRSS

🔒
❌ Acerca de FreshRSS
Hay nuevos artículos disponibles. Pincha para refrescar la página.
AnteayerTus fuentes RSS

CARE study: prospective cohort study on supportive care among paediatric oncology patients in western Kenya--a study protocol

Por: Gichemi · A. · Wijnen · N. E. · Kormelink · E. · Osore · I. · Odero · L. · Olbara · G. · Voskuijl · W. · Nessle · C. N. · van der Bruggen · J.-T. T. · Sieswerda · E. · Serem · E. · Kaspers · G. · Njuguna · F. · Huibers · M.
Introduction

Childhood cancer presents significant challenges in low- and middle-income countries (LMICs), as survival rates remain substantially low. Supportive care, including nutritional support and infection prevention plus management, is crucial in improving outcomes of childhood cancer patients. To develop evidence-based interventions improving supportive care and survival, insight is needed into local prevalences of malnutrition, colonisation and infections, their association with clinical outcomes and the attitude of parents or legal guardians towards nutritional care and infection prevention. The overall aim of this prospective cohort study is to identify modifiable nutritional and infection-related determinants of clinical outcomes at 6 months in children with cancer (1–15 years of age) treated with curative intent at the Paediatric Oncology ward of the Shoe4Africa Children’s Hospital at the Moi Teaching and Referral Hospital in Eldoret, Kenya.

Methods and analysis

We will conduct a prospective cohort study on 150 children aged 1–15 years who are newly diagnosed with cancer and treated with curative intent. During 6 months of follow-up, we will collect clinical data, perform nutritional assessments and monitor pathogen exposure, colonisation and infections. Parents or legal guardians will receive one questionnaire to assess attitudes towards supportive care. Six-month mortality is the primary outcome. Other outcomes include the prevalence and characteristics of malnutrition, rectal colonisation with bacterial and fungal pathogens, infections and neutropenic fever episodes. Statistical analyses will include descriptive statistics, chi-square tests, logistic regression and thematic analysis.

Ethics and dissemination

The Institutional Research and Ethics Committee has approved the study protocol (FAN: 0004674, protocol version 1.0). Informed consent from parents or legal guardians and assent from children ≥12 years will be obtained. Findings will be disseminated through peer-reviewed publications, presentations at academic conferences and engagement with local and national policymakers and stakeholders. Data from this study could guide the development of locally informed, evidence-based supportive care interventions, with the ultimate goal to improve overall survival for children with cancer in LMICs.

Association between depression, anxiety and loneliness with internet addictions among public university students in Malaysia

Por: Muhamad · N. A. · Maamor · N. H. · Tengku Baharudin Shah · T. P. N. · Jamalluddin · N. H. · Leman · F. N. · Rosli · I. A. · Nik Azhan · N. A. F. · Chemi · N. · Muhamad Rasat · M. A. · Abdullah · N. · Abdul Jabbar · N. · Ibrahim · N. · Mohamad Isa · M. F.
Objective

To determine the prevalence of internet addiction and examine its association with psychological factors specifically depression, anxiety and loneliness among Malaysian public university students.

Design

Cross-sectional study.

Setting

All public universities in Malaysia, 20 universities.

Participants

The study included 7278 students from 20 public universities in Malaysia.

Main outcome measures

Statistical analyses were performed usingSTATA V.17 software. Descriptive statistics summarised participants’ demographic characteristics, prevalence of internet addiction and psychological distress (depression, anxiety and loneliness). Pearson’s correlation was used to assess bivariate relationships between internet addiction and psychological variables, while multiple logistic regression identified independent factors associated with internet addiction after adjusting for significant confounders.

Results

The study found that 38.6% of the students showed signs of internet addiction, along with a high level of psychological distress; 24.8% had depressive symptoms, 32.4% experienced anxiety and 35.5% reported loneliness. Moderate positive correlations were observed between internet addiction and depression, anxiety and loneliness (p

Conclusion

The findings indicate significant associations between internet addiction and psychological factors such as depression, anxiety and loneliness. A comprehensive, multifaceted approach is essential to address psychological distress among university students and reduce the risk of internet addiction.

❌