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To identify latent profiles of hospital nurses based on the combination of occupational demands, psychological symptoms and psychological flexibility. Examine how these profiles relate to job turnover intentions.
Cross-sectional online survey.
Registered nurses in France completed an online questionnaire between June and August 2024. The questionnaire covered various aspects of job satisfaction and stress. A non-hierarchical cluster analysis was then conducted on 12 standardised variables to derive profiles. Next, appropriate group-comparison tests and sensitivity checks were performed. No abbreviations or references are used here.
Two profiles emerged. One profile showed a higher workload, greater emotional demands, increased stress and psychological distress, burnout and a lower level of psychological flexibility, as well as a higher intention to leave. The other profile showed lower demands and symptoms, higher psychological flexibility and a lower intention to leave. Group differences on core variables were statistically significant and sensitivity analyses indicated a stable solution.
Person-centred profiles reveal distinct combinations of demands, symptoms and psychological flexibility meaningfully linked to nurses' intention to leave. These findings suggest opportunities for targeted organisational adjustments and brief skills training to strengthen psychological flexibility and retention.
Health-service leaders can use brief screening to identify at risk profiles and align interventions. Policymakers can consider staff and scheduling policies to reduce demand in high-risk units. Educators can incorporate psychological skills into training programmes to promote workforce sustainability.
Fluid overload (FO) is a common complication following cardiac surgery with cardiopulmonary bypass (CPB) and is associated with increased morbidity and mortality. Loop diuretics, particularly furosemide, are widely used to promote sodium and water excretion, but their postoperative use remains largely empirical. International guidelines recommend early assessment of diuretic response using spot urinary sodium concentration, traditionally measured by automated laboratory analysers. Recent advances now enable bedside measurement of natriuresis using point-of-care (POC) urinary sodium sensors. This trial aims to determine whether real-time bedside natriuresis monitoring using a POC device can guide safer and more effective diuretic strategies in the postoperative management of FO.
The EASY-CS trial is a prospective, single-centre, open-label, randomised controlled trial designed to evaluate whether a natriuresis-guided furosemide titration protocol improves diuresis within 48 hours following cardiac surgery with CPB. A total of 102 adult patients undergoing elective cardiac surgery with CPB and requiring postoperative intravenous (IV) furosemide for FO will be randomised in a 1:1 ratio to either standard care (n=51; furosemide titration based on clinical judgement) or a natriuresis-guided arm (n=51), in which furosemide dosing is adjusted according to urinary sodium concentration. All patients will receive an initial 20 mg dose of IV furosemide. In the intervention group, urinary sodium will be measured every 6 hours using a POC sodium sensor (LAQUAtwin Na+ metre, Horiba, Japan). If the spot urinary sodium is
Secondary outcomes include urinary sodium concentration and urine output at 24 hours, natriuresis at 48 hours, and the venous excess ultrasound score at 48 hours, as determined by transthoracic echocardiography. The study will also assess total loop diuretic dose administered, cumulative fluid balance over 48 hours and the incidence of postoperative complications at day 30, including cardiovascular, renal, respiratory and gastrointestinal events. Safety endpoints include the presence of hypotension, hypokalaemia or acute kidney injury before each diuretic administration. Randomisation will be stratified by EuroSCORE II (
Ethical approval has been obtained from the Institutional Review Board (IRB) of Amiens University hospital (IRB-ID: 2025-A00925-44). The study’s results will be disseminated through peer-reviewed publications and presentations at national and international conferences.
ClinicalTrials.gov Identifier: NCT07077772.
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