Audiovisual arts interventions show promise for youth mental health promotion, but evidence remains limited. This scoping review aims to systematically map evidence on audiovisual arts interventions for mental health promotion among youth aged 15–24 years.

The review will be conducted according to the Joanna Briggs Institute guide on evidence synthesis, and the results will be reported following the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for scoping reviews. A comprehensive search will be conducted in seven electronic databases: Web of Science Core Collection (including MEDLINE and ProQuest), PubMed, Embase, Scopus, APA PsycInfo, Communication & Mass Media Complete and China National Knowledge Infrastructure. Grey literature sources, including WHO Institutional Repository for Information Sharing, will also be searched. The search will include publications from 1 January 2000 to 31 December 2025, with no language restrictions. Two reviewers will independently screen titles, abstracts and full texts, and chart data from included studies. The data will be synthesised using a narrative approach.

No ethical approval required as only published data will be analysed. Results will be disseminated through peer-reviewed publications, conferences and stakeholder engagement.

Open Science Framework registration DOI: https://doi.org/10.17605/OSF.IO/DEGPJ.

To investigate the educational value of combining intraoperative explanations with laparoscopic surgical video reviews for teaching the local anatomy of the stomach.

Thirty resident physicians undergoing standardised training in our hospital, including undergraduate resident physicians and clinical-type postgraduates in surgery who had not participated in radical gastrectomy for gastric cancer, were selected as study subjects. They were randomly divided into an experimental group and a control group, with 15 participants in each group. The experimental group received instruction through intraoperative explanations combined with laparoscopic surgical video reviews, while the control group participated in surgery without additional instructional methods. After the teaching sessions, both groups underwent clinical practice assessments, theoretical examinations and evaluations of teaching satisfaction. The distribution of the data was assessed using the Shapiro-Wilk normality test along with Quantile-Quantile plots. Two-way analysis of variance was employed to evaluate the main effects and interaction effects of clinical practice scores across different groups and student types. Statistical power was examined through post hoc power analysis.

The clinical practice assessment results, theoretical examination scores and teaching satisfaction ratings of the experimental group were significantly higher than those of the control group, with all differences reaching statistical significance (p

Combining intraoperative explanations with laparoscopic surgical video reviews for teaching local anatomy during distal gastrectomy is more effective than participation in surgery alone. This approach allows students to review surgical videos at their convenience, enhancing their understanding and mastery of local anatomical structures and significantly improving the quality of local anatomy education for resident physicians.

Oesophageal squamous cell carcinoma (ESCC) ranks among the most aggressive malignancies and carries a poor prognosis. Lymphocytes play a key role in combating infections and suppressing tumourigenesis. Many studies have established a close association between lymphocyte depletion and adverse therapeutic outcomes in oesophageal cancer. Nevertheless, high-quality data validating the clinical efficacy and safety of lymphocyte-sparing thoracic radiotherapy regimens for ESCC remain scarce.

This prospective, open-label, randomised controlled trial aims to determine whether lympho-nTRT-ESO reduces the incidence of acute grade 3–4 lymphopaenia in patients with ESCC undergoing neoadjuvant chemoradiotherapy (nCRT), compared with conventional thoracic radiotherapy (RT). A total of 212 participants will be enrolled and randomly allocated in a 1:1 ratio to either the lymphocyte-sparing RT (RT) group or the conventional RT group. All patients will receive standardised nCRT, which will deliver a total dose of 41.4 Gy in 23 fractions. For the lymphocyte-sparing RT group, RT planning prioritises the planning target volume (PTV) coverage and conventional organ-at-risk (OAR) constraints while applying dose constraints to lymphocyte-related OARs (LOARs). These LOARs include the T1–T12 vertebral bodies, ribs, spleen and major cardiovascular structures (heart and large blood vessels), with optimisation performed only after PTV coverage and standard OAR constraints are satisfied.

This trial was approved by the Ethics Committee of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine (RJ 2024–210) on 11 July 2024 and registered on ClinicalTrials.gov (NCT06596954) before participant recruitment. All participants should provide written informed consent to be eligible. We planed to publish the primary and secondary results of this study in scientific peer-reviewed journals and present at radiation oncology conferences.

NCT06596954

At present, the available evidence regarding the relationship between prone position ventilation (PPV) and tracheal injury score remains inadequate. This study seeks to gain deeper insights into the relationship between PPV and tracheal injury score in intensive care unit (ICU) patients with invasive ventilation.

A secondary analysis of a prospective cohort study.

Our study was conducted in a Class III hospital in Hebei Province, China.

Patients aged over 18 years admitted to the ICU between 31 May 2020 and 10 November 2023 with a tracheal tube and expected to be on the tube for more than 24 hours.

The primary outcome was tracheal injury score, assessed via fibreoptic bronchoscopy for hyperaemia, ischaemia, ulcers and perforation. Lesions were classified as moderate, severe or confluent based on extent.

Among the 149 selected participants, the average age was 58.4±16.2 years, with 65.8% being male. The results of adjusted linear regression showed that PPV was associated with tracheal injury scores (β: 5.33; 95% CI 3.84 to 6.82). Subgroup analysis indicated that PPV is significantly associated with an increased tracheal injury score, and this association remains consistent across different ages, sex, septic shock and non-septic shock groups, and duration of intubation

Our findings suggest PPV may be associated with tracheal injury score, highlighting a potential link between PPV and tracheal injury score.

ChiCTR2000037842, registered 3 September 2020 retrospectively registered, https://www.chictr.org.cn/showproj.html?proj=57011.

Agents used in antitumour therapy have toxic effects on the cardiovascular system of breast cancer (BC) patients, increasing the risk of cardiovascular disease, which has become the most common non-cancer cause of death in BC patients. Exercise can effectively prevent or reduce the occurrence of cardiotoxicity, however, most BC patients have low levels of physical activity. The Health Action Process Approach (HAPA) model has been successfully applied to encourage patients to adhere to physical exercise. This study aims to explore the impact of exercise interventions based on the HAPA model on the monitoring indicators related to cardiotoxicity in BC patients during chemotherapy, aiming to prevent cardiotoxicity in BC patients and improve their physical activity level, exercise self-efficacy, exercise social support and exercise compliance.

In a protocol for a quasi-randomised controlled trial involving a 4-month intervention, 62 patients with BC will be recruited from a tertiary care centre in China. Participants from the first oncology department will be assigned to the HAPA model-based exercise intervention group (n=31), while participants from the second oncology department will be assigned to the control group that will receive standard exercise guidance (n=31). The primary outcome will be the incidence of cardiotoxicity assessed by Electrocardiogram (ECG). The secondary outcomes will include physical activity level, exercise self-efficacy, exercise social support and exercise compliance, which will be evaluated by the short form of the International Physical Activity Questionnaire (IPAQ-SF), Self-Efficacy for Exercise Scale (SEE), Social Support Scale for Exercise (SSSE), and percentage of achieving the recommended total time of exercise per week. The chi-square test or Mann-Whitney U tests will be applied to compare the differences in ECG results and exercise compliance between the two groups. To evaluate the effect of exercise intervention on IPAQ-SF, SSE and SSSE, repeated measures ANOVA will be employed to examine the group-by-time interactions and main effects.

This study has been approved by the Ethics Committee of the First Affiliated Hospital of Dalian Medical University (PJ-KS-KY-2024-267(X)). The results of this study will be published via peer-reviewed publications and presentations at conferences.

ChiCTR2400090672.

Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterised by heterogeneous motor and non-motor symptoms. The classification of PD into distinct subtypes remains a major challenge, limiting the development of precision medicine approaches. Existing subtyping methods have relied on clinical features, genetic markers or isolated biomarkers, but an integrated classification system incorporating neuroimaging and fluid biomarkers is lacking. The Prospective Assessments with Neuroimaging and fluid Data Analysis in PD (PANDA) study is a single-centre, longitudinal cohort study designed to explore PD heterogeneity by integrating multimodal neuroimaging, fluid biomarkers and comprehensive clinical assessments.

The PANDA study aims to recruit 500 PD patients and 100 healthy controls (HC) at Guangdong Provincial People’s Hospital from March 2021 to July 2026. Participants undergo three study visits: baseline, 2-year and 4-year follow-ups. Data collection includes brain MRI scans, blood and cerebrospinal fluid sampling, clinical scales, gait assessment, ambulatory blood pressure monitoring and eye-tracking evaluations. A standardised electronic data capture system ensures data accuracy and completeness. The primary objective is to identify biologically and neuroimaging-defined PD subtypes, track disease progression and explore potential biomarkers for stratification. Statistical analyses will include data-driven clustering techniques and longitudinal modelling to assess subtype stability over time.

The PANDA study has been approved by the Institutional Review Board of Guangdong Provincial People’s Hospital (No KY2024-719-01) and is conducted in accordance with the Declaration of Helsinki. Written informed consent is obtained from all participants or their legal guardians prior to study enrolment. The findings from this study will be disseminated through peer-reviewed journals and conference presentations, ensuring accessibility to researchers, clinicians and stakeholders involved in PD research and treatment.

ChiCTR2400091709.

Tetanus is associated with very high mortality, but there is currently no consensus on the mortality and risk factors for hospitalised adult patients with tetanus. Therefore, we conducted this systematic review and meta-analysis to explore the mortality and associated risk factors in hospitalised adult patients with tetanus.

Systematic review and meta-analysis.

PubMed, Web of Science, The Cochrane Library and Embase, covering the period from 1 January 2000 to 5 February 2024.

Observational studies with a focus on the mortality and associated risk factors in hospitalised adult patients with tetanus.

Two researchers independently reviewed the studies and extracted the data. The pooled effect sizes for mortality and the total number of hospitalised patients with tetanus were calculated, along with the overall pooled mortality and corresponding 95% CI. Risk factors for mortality were determined using relative risk (RR) and 95% CI. The I² statistic was calculated to describe heterogeneity between studies. Additionally, subgroup and meta-regression analyses were carried out to further explore potential sources of heterogeneity. All statistical analyses were conducted via StataSE V.15.0.

A total of 22 studies were included, comprising 1618 hospitalised adult patients with tetanus. The overall mortality among hospitalised adult patients with tetanus was 32.0% (95% CI: 27.1% to 37.0%). Six risk factors associated with mortality in these patients were identified, including age ≥40 years (RR=1.89, 95% CI: 1.37 to 2.61), incubation period

The study findings have important implications for clinical practice and public health policy. The high mortality underscored the urgent need to strengthen tetanus prevention strategies, particularly by increasing vaccination coverage and enhancing wound care education in adults aged ≥40 years. The six identified mortality risk factors provided a framework for early risk stratification and targeted interventions in hospitalised patients with tetanus. Meanwhile, more well-designed, large-scale studies are needed for further validation and exploration.

CRD42024533554.

The transition from paediatric to adult healthcare marks a pivotal period for chronically ill adolescents, as they transition from a highly supportive and family-oriented environment to an adult-oriented and a more individual-oriented healthcare system that places a greater emphasis on personal responsibility and independence. Parents, given their firsthand experience managing their child’s healthcare, play a central role in ensuring a smooth and successful transition, yet their perspectives on the barriers and facilitators of this complex process remain vastly underexplored. This scoping review aims to assess and provide comprehensive insights into parents’ perceptions of the successes and challenges during their adolescents’ transition from paediatric to adult healthcare.

This scoping review is led by patient partners and will be guided by the Peters et al and the Joanna Briggs Institute guidelines for scoping reviews. The preliminary search strategy will be developed and calibrated in Ovid MEDLINE and will be subsequently replicated in the Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsychInfo, Embase, Web of Science and Sociological Abstracts from inception through 18 December 2024, including all types of studies. Grey literature sources recommended by patient partners and clinical and qualitative research experts will also be included. Two reviewers will independently perform the title and abstract review of all studies against the predefined inclusion and exclusion criteria, followed by the full-text review of included studies. The reference list of all included studies will also be screened to maximise the retrieval of relevant sources. Data will be extracted and analysed quantitatively and qualitatively, with the study procedural and reporting format following Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews guidelines.

This scoping review, through the broad and systematic mapping of existing literature, aims to provide a foundation for developing targeted support systems, strategies and interventions to address the unique needs and barriers faced by parents and caregivers of chronically ill adolescents during this critical transition to adult care.

Ventral hernia repair is among the most commonly performed general surgical procedures, during which meshes are often used to provide further support to weakened or damaged tissue surrounding the hernia repair site. Slowly resorbable synthetic meshes have recently emerged as a valid choice, as confirmed by published clinical evidence on launched meshes in the repair of ventral hernias showing satisfactory results. This study was designed to assess the performance and safety of a newly developed slowly fully resorbable self-gripping synthetic mesh in patients undergoing ventral hernia repair through open surgery in clean and clean-contaminated fields.

This is a prospective, multicentre, single-arm study that will be conducted in up to 20 European and US sites with a total of 163 patients undergoing midline primary or incisional ventral hernia repair in clean or clean-contaminated surgical fields using an open surgical approach and implanted with Transorb self-gripping resorbable mesh in retrorectus placement with or without transversus abdominis release. The study will include patients ≥18 years old, presenting at least one risk factor impairing wound healing. The primary endpoint will be hernia recurrence rate within 12 months, postoperatively evaluated by physical exam; secondary endpoints will include hernia recurrence rate within 1 month, 6 months, 24 months, 36 months, 48 months and 60 months postoperatively, hernia recurrence rate resulting in reoperation, hernia recurrence rate reported by patients, time to hernia recurrence, rate of surgical site occurrence (SSO), rate of SSO requiring procedural interventions, surgeon satisfaction and change in patient-reported pain and quality of life. The study will be considered successful if the upper limit of the 95% Bayesian credible interval for the primary endpoint is less than 14.2%. Descriptive statistics will be used to summarise secondary study endpoints unless otherwise noted.

The multicentre, single-arm, prospective study of Transorb self-gripping resorbable mesh in subjects undergoing open repair of ventral hernia study will be conducted in compliance with the Good Clinical Practice standards, ISO 14155:2020 and the Declaration of Helsinki. The publication plan includes dissemination of the 12-month, 24-month, 36-month, 48-month and 60 month study results.

The RECOVER study has been registered at clinicaltrials.gov (NCT06449378).

Forensic mental health nursing (FMHN) is a subspeciality of psychiatric nursing. An area of mental health nursing care that is situated at the intersection of health, social and criminal justice systems. Over the past two decades, FMHN has evolved beyond custodial and containment practice. Contemporary FMHN has an emphasis on therapeutic interventions, identifying patients as partners in care and nursed through a trauma-informed, recovery-orientated lens. Numerous scholars have examined the role of the FMHN and its inherent complexities. However, much of the existing literature is outdated and is limited in scope, describing the role and responsibilities of an FMHN relevant to contemporary practice. This paper maps the literature over the last 20 years to establish what explicitly defines the modern FMHN, specifically examining factors that have shaped the role and influenced patient outcomes and care delivery; including areas of good practice.

In line with the Joanna Briggs Institute (JBI) guidance on scoping reviews, including Arksey and O’Malley’s (2005) five-step framework, we will conduct a search within MEDLINE (EBSCO), CINAHL (EBSCO), PsycINFO (Ovid) and the Cochrane Database of Systematic Reviews and Cochrane Central Register of Controlled Trials in the Cochrane Library. The first author conducted a preliminary search in October 2024 to identify literature in this area and a review of keywords to develop the foundation search strategy. The search strategy was constructed in the MEDLINE (EBSCO) database May 2025 by the lead author and an information specialist/librarian. Eligibility criteria of publications written in English, with a date range of 2004–2024, including the first quarter of 2025, forensic mental health nurse population and secure inpatient settings. All extracted literature will be exported into EndNote V.21 in order to support the removal of duplicates and assist in the screening and selection process. A two-step data selection process will include stage one, where two authors independently conduct a preliminary title and abstract screen of all extracted data using a data extraction instrument developed per JBI scoping review guidance. Each paper will be categorised as ‘yes’, ‘no’ or ‘maybe’. Step two: All documents categorised as ‘yes’ or ‘maybe’ will undergo a full-text screening. Narrative summaries and tables will present the results in full.

This scoping review will analyse existing published data; therefore, ethical approval is not required. The findings of this review will be presented at local and international conferences and published in peer-reviewed journals. The formal search will commence in June 2025, with an aim to submit in full for peer-review publication by October 2025.

Obesity is a growing public health issue worldwide, and anxiety is a major psychological disorder associated with obesity. Electroacupuncture (EA) has been proven to be a feasible treatment modality for obesity and anxiety in clinical practice. However, data on the effectiveness of EA for anxiety patients with obesity are lacking. Therefore, this study aimed to evaluate the effectiveness and safety of EA for anxiety in patients with obesity and to observe the brain functional status of the patients and the intervention effects of EA on brain function by using functional MRI (fMRI).

In this randomised, blinded, sham-controlled clinical trial, 72 patients with obesity from two hospitals with anxiety will be randomly divided into EA and control groups in a 1:1 ratio by using a random number table. Patients in the EA group will receive EA treatment with penetrating needling at specific acupoints for 8 weeks. The control group will receive Park’s acupuncture with non-penetrating needling. Weight, waist, body mass index, Self-rating Anxiety Scale score, State-Trait Anxiety Inventory score and Pittsburgh Sleep Quality Index will be measured before treatment, after 8 weeks of treatment and at the 1-month follow-up evaluation. Objective metabolic parameters such as triglyceride, total cholesterol, fasting blood glucose, ghrelin, leptin, cortisol and adrenocorticotropic hormone levels will also be measured before and after the 8-week intervention. 20 patients will be randomly selected from the EA and control groups before treatment. These randomly selected patients will undergo fMRI scans before and after treatment. Regional homogeneity, amplitude of low-frequency fluctuation and resting-state functional connectivity will be evaluated to compare the dysfunctional brain regions between two groups of patients after treatment.

The study protocol has been approved by the Hospital Ethics Committee of Second Affiliated Hospital of Anhui University of Chinese Medicine (2023-zj-42). Informed consent will be obtained prior to starting study-related procedures. The results will be disseminated in peer-reviewed journals and at scientific conferences.

Chinese Clinical Trial Registry. ChiCTR2400083594, registered 29 April 2024.

Various psychological, cognitive, behavioural, medication and neurostimulation treatments can improve the outcomes of people with depressive and anxiety disorders. However, in usual practice, there is large variability in treatment delivery and treatments are poorly characterised. The effectiveness and quality of mental health services in the community are not accurately monitored and are poorly understood. At present, healthcare organisations, payers and policy makers know little about the quality of care they support. Similarly, patients and families have limited information on quality to guide choice of provider or organisation. It will be necessary to implement monitoring of treatment quality so that treatment and outcomes can be improved. This study develops, tests and validates a new, transdiagnostic outcome-focused mental health quality measure. This measure is based on routine, regular patient reports of their symptoms. It is designed to be aggregated at the provider, clinic, organisation or plan level; inform choice of provider; and be used to improve routine delivery of services and quality of care among patients with common psychiatric disorders.

The project analyses existing data with responses to a wide variety of items that are known to assess depression or anxiety and empirically selects symptom items for a transdiagnostic outcome-focused quality measure. The project informs risk adjustment and benchmarking of the quality measure by studying how patient, provider and practice factors, including health-related social needs, baseline symptom severity and diagnoses, affect outcomes. Drawing on these, the project specifies an outcome-focused quality measure that includes risk adjustment and benchmarks for improvement; and studies, at practices nationally, its feasibility and psychometric properties, the effect of treatment characteristics on the quality of care, and the effect of quality on health-related quality of life.

Results will be published. The quality measure is designed to be broadly relevant across community settings and populations and to be submitted for endorsement by regulatory and governing bodies.

The Asian American, Native Hawaiian and Pacific Islander (AANHPI) community is the fastest-growing racial/ethnic population in the USA. Previous research identified that medical students perceived a lack of exposure to AANHPI patients and topics in medical school curricula; however, there remains a lack of potential interventions to address this need. The goal of our study is to present a case study for identifying interventions in medical school curricula that improve cultural humility-based training for providing medical care for AANHPI populations.

In this qualitative study, authors conducted four virtual focus groups with 15 medical students at a single institution to identify curricular interventions. The authors then conducted virtual semistructured interviews with eight medical educators one-on-one to explore the feasibility of the proposed interventions. Data were analysed using qualitative thematic analysis, and analysis was performed with ATLAS.ti.

Medical students and medical educators based at medical institutions in the USA.

15 medical students and eight medical educators participated in the study.

All medical students (n=15) and educators (n=8) noted that there is limited engagement of AANHPI communities in current medical curricula and limited curricular components that address the diversity within the AANHPI umbrella. Medical student focus groups identified three interventions to improve cultural humility-based training for treating AANHPI patients: reflection spaces, community engagement and clinical training on documenting cultural needs. Educators supported the feasibility and importance of these interventions to prepare students to work with not only AANHPI patients but also with patients of other diverse backgrounds.

AANHPIs represent a heterogeneous population consisting of unique cultural heritages. Our research demonstrates the importance of highlighting this community in cultural humility curricula to provide an example of how to consider and appreciate diversity in patient populations. In this paper, we present student and medical educator-supported curricular interventions that not only increase awareness of issues impacting AANHPI communities, but also emphasise building skills of self-reflection, lifelong learning and empathy that are applicable to patients of all backgrounds.