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Adverse childhood experiences and COVID-19 vaccination uptake: Examining the intersection of sex and urban-rural residence

by Karyn Fu, Dylan B. Jackson, Alexander Testa

Background

Adverse childhood experiences (ACEs) have been linked to negative health outcomes and behaviors in adulthood. Despite widespread research on ACEs, their relationship with COVID-19 vaccination uptake, particularly heterogeneity across demographic groups, remains underexplored. This study examined the association between ACEs and COVID-19 vaccination status, with a focus on how this relationship varies by sex and urban-rural residence.

Methods

Data were obtained from the 2022 Behavioral Risk Factor Surveillance System (BRFSS), including respondents who participated in the ACEs and COVID-19 vaccination optional state modules (N = 12,085 adults). COVID-19 vaccination status (yes/no) served as the dependent variable, while ACEs were categorized into four levels: 0, 1, 2–3, and 4 + ACEs. Multivariable logistic regression analyses, stratified by sex and urban-rural residence, were conducted to assess the association between ACEs and vaccination status.

Results

Among the sample, 76.2% reported receiving at least one dose of the COVID-19 vaccine. Multivariable analysis revealed no statistically significant association between ACEs and vaccination status for the full sample. Stratified analyses indicated that male respondents living in rural counties with 4 + ACEs had significantly lower odds of vaccination (adjusted odds ratio [aOR] = 0.57, 95% CI = 0.34–0.96). No significant associations were observed for other demographic groups (e.g., females in urban or rural areas; males in urban areas).

Conclusions

The findings suggest that males in rural areas with high ACE exposure may be vulnerable to low COVID-19 vaccination uptake. Targeted trauma-informed public health interventions warrant consideration to address vaccination uptake among this population.

Methods of measuring body image disturbance in eating disorders: a scoping review protocol

Por: De Simone · M. · Mazza · A. · Job · M. · Testa · M.
Introduction

Body image disturbance (BID) is a complex construct that includes cognitive-affective, perceptual and behavioural characteristics, influencing how people perceive and feel about their bodies. An accurate assessment of BID is important for identifying and treating eating disorders (EDs), debilitating psychiatric conditions that compromise individuals’ well-being, leading to high death rates. Methods used to quantify BID in people with EDs vary widely, making it difficult to establish a gold standard measure. Hence, this scoping review will aim at summarising the literature on the methods to assess BID in people with EDs, providing a clearer overview of the topic.

Methods and analysis

The scoping review will map and synthesise the BID in individuals with EDs, exploring: (1) Which methods and tools are used to assess BID in individuals with EDs, and are they self-reported or evaluated by clinicians? (2) Which components of BID are assessed? (3) What are the main outcomes measured by these methods and tools? What is their validity, reliability and sensitivity? The population of interest will include individuals of all ages diagnosed with one of the main EDs: anorexia nervosa, bulimia nervosa and binge ED (BED). Hence, the concept of this review will revolve around the methods and tools for measuring BID in EDs focusing on research conducted either in experimental or clinical settings. Records will be screened by two independent reviewers and any discrepancies will be resolved by a third reviewer. Results will be synthesised and reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The search is planned to be conducted from November 2025 to September 2026 through multiple databases, including PubMed, PsycINFO, ScienceDirect, Web of Science, PubMed Central and Scopus.

Ethics and dissemination

Formal ethical approval is not required for this review. The results will provide a clear overview of the assessment methods for BID in EDs. Findings will be disseminated through publication, and presentations at relevant scientific conferences and sharing with professional networks.

Needs, barriers and facilitators for a healthier lifestyle in haemodialysis patients: The GoodRENal project

Abstract

Background

Malnutrition, sedentary lifestyle, cognitive dysfunction and poor psychological well-being are often reported in patients on haemodialysis (HD).

Aims

We aimed to explore needs, barriers and facilitators—as perceived by patients, their carers, and healthcare professionals (HCPs) for increasing the adherence to the diet, to physical activity and cognition and psychological well-being.

Methods

This is an observational cross-sectional study following the STROBE statement. This study is part of an ERASMUS+ project, GoodRENal—aiming to develop digital tools as an educational approach to patients on HD. For that, the GoodRENal comprises HD centers located in four Belgium, Greece, Spain and Sweden. Exploratory questionnaires were developed regarding the perceived needs, barriers and facilitators regarding the diet, physical activity, cognition and psychological well-being from the perspective of patients, their carers and HCPs.

Results

In total, 38 patients, 34 carers and 38 HCPs were included. Nutrition: For patients and carers, the main needs to adhere to the diet included learning more about nutrients and minerals. For patients, the main barrier was not being able to eat what they like. Physical activity: As needs it was reported information about type of appropriate physical activity, while fatigue was listed as the main barrier. For Cognitive and emotional state, it was perceived as positive for patients and carers perception but not for HCPs. The HCPs identified as needs working as a team, having access to specialised HCP and being able to talk to patients in private.

Conclusions

Patients and their carers listed as needs guidance regarding nutrition and physical activity but were positive with their cognitive and emotional state. The HCPs corroborated these needs and emphasised the importance of teamwork and expert support.

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