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Hoy — Diciembre 16th 2025Tus fuentes RSS

Updated surviving sepsis campaign guidelines enable tailored approach to antibiotic timing as validated in real-world settings

Por: Parappil · S. H. · Basheer · A.

Commentary on: Taylor SP, Kowalkowski MA, Skewes S, Chou SH. Real-world implications of updated surviving sepsis campaign antibiotic timing recommendations. Crit Care Med. 2024 doi: 10.1097/CCM.0000000000006240.

Implications for practice and research

  • Antibiotic delivery in suspected sepsis must be prioritised within the clinical context emphasising the need to individualise antibiotic timing according to patient profiles.

  • In the absence of shock, a more lenient approach to antibiotic timing could support the rational use of antibiotics.

    • Context

    Sepsis is a life-threatening response to infection and remains a critical challenge with high morbidity and mortality rates. The Surviving Sepsis Campaign (SSC) guidelines serve as a cornerstone for sepsis management and are pivotal in standardising care. Taylor et al’s article1 scrutinises the real-world implications of updated SSC antibiotic timing recommendations2 and offers critical insights into the practical effects of the revised antibiotic timing guidelines.

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