This study aims to explore how age and gender are associated with health deterioration related to caregiving among caregivers aged 75 and older in Spain.

Observational, descriptive, cross-sectional study.

Nationwide survey in Spain: 2020 Survey on Disability, Personal Autonomy and Situations of Dependency.

All non-professional caregivers identified by the survey (3746): 3166 caregivers younger than 75 (CG75–) and 580 caregivers 75 years old or older (CG75+).

Self-reported caregivers’ health deterioration, as a categorical variable (present or absent).

The majority of caregivers in both groups were women (63.2% of CG75– and 57.0% of CG75+, p=0.011). CG75+ provided care 16 hours/day (vs 14.1 hours/day of CG75–, p=0.032). Over half of CG75+ reported health deterioration (53.0%), compared with 43.5% of CG75– (p

In Spain, older caregivers have a specific socio-demographic profile, provide high-intensity care and report a higher caregiving-related health deterioration. However, the association between older age and health deterioration was found only in women. Public health interventions must prioritise older female caregivers.