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This study aimed to (1) implement a Safety Protocol of Thirst Management (SPTM) as an evidence-based practice for quenching postoperative thirst and (2) evaluate its effectiveness using a comparative pre-and-post induction design.
A quasi-experimental study using propensity scored matching.
Guided by the Iowa Model, the SPTM was implemented at a tertiary medical centre in Taiwan in 2023. Outcomes were compared between adult surgical patients admitted in 2023 (post-induction) and those admitted prior (pre-induction). Data on thirst and pain intensity, body temperature, and PACU length of stay (LOS) were analyzed for 15,168 patients.
A standardized SPTM flow diagram was established. Following SPTM induction, mean thirst scores significantly decreased from 5.76 to 1.30 (p < 0.001). Although pain intensity and PACU LOS (63.63 vs. 62.23 min) showed statistically significant increases, these changes were clinically marginal. Body temperature remained stable with no incidence of perioperative hypothermia.
The Iowa Model effectively guides nursing organizations in translating evidence into practice. The SPTM provides a safe, consistent framework for nurses to alleviate postoperative thirst, significantly enhancing the quality of surgical care.
This study addresses the lack of standardized thirst management. Results demonstrate that an evidence-based SPTM protocol effectively quenches thirst without increasing adverse clinical risks.
The SPTM was triggered by patient reports of thirst-related distress. During the design phase, patient feedback on the acceptability of cold oral stimuli was used to refine the protocol. While patients did not participate in the data analysis, the primary outcome (thirst intensity) was selected based on its significance to patient-cantered care.
This study was reported according to TIDieR guideline.
To explore parents' experience when their children underwent emergence delirium during anaesthesia recovery.
A descriptive phenomenological qualitative study.
This descriptive phenomenological study was conducted at a medical center in Taiwan. Purposive sampling was employed, and a semi-structured interview guide was used to conduct in-depth interviews. Twelve parents whose children experienced emergence delirium were recruited after data saturation was reached. Data were collected between January and July 2024 and analysed using Colaizzi's seven-step method.
Parents underwent an unexpected journey characterised by emotional ups and downs when witnessing their child's emergence delirium. Four major themes were generated, including ‘unexpected chaos’, describing the disorienting situation parents experienced when confronted with their child's unfamiliar behaviours; ‘help beyond reach’, reflecting their inability to provide comfort despite being physically present; ‘a day of suffering’, highlighting the emotional overwhelm during the emergence delirium episode; and ‘appreciation after recovery’, illustrating their relief and gratitude once their child returned to baseline. These themes reveal the intense emotional fluctuations parents experience during this critical phase.
This study highlights the complex emotional fluctuations parents experience when facing their child's emergence delirium. The findings emphasise the need for anticipatory guidance and support strategies to better prepare parents and inform family-centred nursing practices.
This study addresses a gap regarding the emotional challenges experienced by East Asian parents when their child undergoes emergence delirium. The findings reveal complex parental distress shaped by internal worry and external social pressure in shared recovery spaces. These insights inform culturally sensitive care models, emphasising the importance of private environments and communication strategies that reduce parental stress and improve clinical support.
Two parents reviewed and provided feedback on the interview content and results, improving cultural relevance and clarity.
The study followed COREQ guidelines.
Although the positive correlation between self-efficacy and quality of life and the negative correlation between symptom occurrence and self-efficacy are well established in the cancer literature, the underlying mechanism, whether self-efficacy mediates the effect of symptoms on quality of life, remains unclear due to the cross-sectional design of prior studies. Longitudinal investigation is crucial for establishing the causal mechanism of self-efficacy in mitigating the adverse impact of cancer-related symptoms on quality of life.
To examine the longitudinal mediating effect of self-efficacy on the relationship between symptom occurrence and quality of life among 534 cancer patients on treatment with moderate to high symptoms.
This is a secondary data analysis of the longitudinal mediating effect. A sample of patients with moderate to high symptoms on cancer treatments (N = 534) from a randomised controlled trial was used. We adopted a cross-lagged panel model (CLPM) approach to test the longitudinal mediating effect with three waves. The longitudinal invariance of the measurement was previously tested.
The results showed that cancer-coping self-efficacy predicted the following assessment of symptom occurrence, but not vice versa. Also, cancer-coping self-efficacy had an immediate direct impact on quality of life and the influence sustained to the following assessment. Our mediating analysis showed that cancer-coping self-efficacy totally mediated the relationship between symptom occurrence and quality of life (unstandardized β = −0.008, standardised B = −0.036, p = 0.036, CI95 = [−0.001, −0.016]).
Our findings provide initial evidence supporting the causal mechanism of cancer-coping self-efficacy in interventions that aim for symptom management and quality of life improvement.
This study is the first to test the longitudinal mediating mechanism of cancer-coping self-efficacy in the relationship between symptom occurrence and quality of life among the cancer population. Further testing using a randomised controlled trial of a specifically designed self-efficacy-enhancing intervention is needed.
No patient or public contribution.
In Taiwan, engagement in professional help-seeking among persons living with schizophrenia remains limited despite increasing demands on mental healthcare systems. Clarifying the factors that shape professional help-seeking attitudes is essential for promoting recovery-oriented care. This study examined the correlates of professional help-seeking attitudes in persons with schizophrenia in Taiwan.
A cross-sectional correlational study.
A total of 144 persons receiving psychiatric rehabilitation care at three hospitals in Taiwan were recruited. Data were collected using structured self-report measures assessing sociodemographic and clinical characteristics, schizophrenia literacy, internalized stigma, and professional help-seeking attitudes. Descriptive statistics, bivariate analyses, and hierarchical multiple regression analyses were conducted.
Participants generally reported unfavorable attitudes toward professional help-seeking. More favorable attitudes were associated with higher educational attainment, shorter illness duration, greater schizophrenia literacy, and lower internalized stigma. Schizophrenia literacy and internalized stigma showed the most robust relationships with professional help-seeking attitudes.
Within Taiwanese mental healthcare settings, schizophrenia literacy and internalized stigma appear to be central to attitudes toward professional help-seeking among persons living with schizophrenia.
Routine assessment of schizophrenia literacy and internalized stigma, together with culturally sensitive and recovery-oriented nursing interventions, may enhance treatment engagement among persons living with schizophrenia. The findings may also inform mental health nursing practice in other cultural and healthcare contexts where limited schizophrenia literacy, stigma, and long-term inpatient care pose barriers to recovery-oriented care delivery.
The Cancer Behaviour Inventory–Brief Version was designed to assess cancer-coping self-efficacy in clinical and research settings where minimising patient burden is essential. However, there is no evidence of its longitudinal validity. Although widely used in cancer research, the lack of evidence for longitudinal invariance significantly undermines its validity in studies spanning multiple time points. Establishing longitudinal invariance enables valid comparisons over time, enhancing our confidence in applying it in longitudinal research.
To examine the factor structure of the measurement and test its longitudinal invariance across four time points in cancer patients experiencing moderate-to-high symptoms during curative cancer treatment.
A longitudinal psychometric evaluation.
This is a secondary data analysis of a randomised controlled trial in patients with moderate-to-high symptoms undergoing cancer treatment (N = 534). We conducted longitudinal invariance tests for the measurement using four time points. Other psychometric tests included confirmatory factor analysis, reliability analyses and correlations.
Our confirmatory factor analysis supported the four-factor, 12-item structure for the Cancer Behaviour Inventory–Brief Version. Items 1 and 6 were found to be moderately correlated. The resulting 12-item measure demonstrated good internal consistency, with convergent and divergent validity supported by correlations with selected instruments. Finally, longitudinal invariance was tested, which revealed strict measurement invariance across four time points (CFI = 0.930, RMSEA = 0.045, SRMA = 0.056).
We found that the factor structure of the Cancer Behaviour Inventory–Brief Version remained stable over four time points in a sample of patients having moderate to high symptoms under cancer treatment. This supports its accountability for examining the changes in cancer-coping self-efficacy among cancer patients over time in longitudinal studies.
This study confirms that Cancer Behaviour Inventory–Brief Version has adequate internal consistency and demonstrated evidence of construct validity. Our conclusion of strict longitudinal invariance supports its credibility for continuous assessment of cancer-coping self-efficacy to evaluate patient outcomes and intervention processes over time in clinical and research settings.
No patient or public contribution.
Acute kidney injury (AKI) is a significant challenge in hospital settings, and accurately differentiating between intrinsic and prerenal AKI is crucial for effective management. The fractional excretion of urea (FEUN) has been proposed as a potential biomarker for this purpose, offering an alternative to traditional markers such as fractional excretion of sodium. This study aimed to assess the diagnostic accuracy of FEUN for differentiating intrinsic from prerenal AKI in hospitalised patients.
We conducted a systematic review and bivariate random effects meta-analysis of diagnostic accuracy studies. The study followed the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.
PubMed, Embase and Cochrane databases were searched from inception to 1 November 2023.
We included observational studies that focused on patient with AKI and reported FEUN data sufficient to reconstruct a complete 2x2 contingency table (true positives, true negatives, false positives and false negatives) for evaluating its diagnostic accuracy.
Two reviewers extracted data, assessed risk of bias with Quality Assessment of Diagnostic Accuracy Studies-2 and graded certainty of evidence using the GRADE approach. Pooled sensitivity, specificity, positive and negative likelihood ratios, and the area under the summary receiver operating characteristic curve (SROC) were calculated; heterogeneity was measured with I². A prespecified subgroup restricted to patients receiving diuretics served as a sensitivity analysis.
12 studies involving 1240 patients were included, with an overall occurrence rate of intrinsic AKI of 38.8%. FEUN had a pooled sensitivity of 0.74 (95% CI 0.60 to 0.84) and specificity of 0.78 (95% CI 0.66 to 0.87), with positive predictive value and negative predictive value of 0.76 (95% CI 0.68 to 0.83) and 0.74 (95% CI 0.66 to 0.81), respectively. The SROC curve showed a pooled diagnostic accuracy of 0.83. Heterogeneity was substantial (I²>90%) for sensitivity and specificity. In a diuretic-only subgroup (six studies) specificity rose to0.87 and heterogeneity declined (I²=56%). Overall certainty of evidence was low owing to inconsistency.
FEUN is a biomarker with moderate diagnostic accuracy for differentiating between intrinsic and prerenal AKI in hospitalised patients. Its application could enhance AKI management; however, the high heterogeneity observed in our study highlights the need for further research to evaluate its utility across diverse patient populations and clinical settings.
CRD42024496083.
To develop a grounded theory that explains how formal care service providers experience caring for and supporting persons with early-onset dementia (EOD).
A grounded theory approach.
Thirty formal care service providers of persons with EOD were recruited from community-based dementia care facilities in northern and central Taiwan from August 2021 and February 2022 using purposive and theoretical sampling. Transcribed face-to-face, semi-structured interview data were analysed with constant comparative analysis. A theoretical framework was constructed from the data to describe the experience of being a formal care service provider for persons with EOD.
The core category of ‘client-as-partner care’ was the theoretical framework that explained the experience of formal care service providers and described how participants met the needs of persons with EOD. Five categories described the components of the process: (1) identifying clients' characteristics; (2) establishing a personal relationship; (3) enhancing self-esteem; (4) maintaining dignity; and (5) the influence of family members and community members. The first four categories were interactive and key to delivering client-as-partner care; the fifth category could alter any key component and reduce or improve the quality of care. Reflections shared by participants offered a window into the outcomes of successful client-as-partner care: quality of life improved for clients and job satisfaction increased for providers.
The client-as-partner care model for persons with EOD required knowledge of the client's unique characteristics, a strong provider-client relationship, offering strategies tailored to the client's abilities and interests, and fostering independence.
Client-as-partner care provides a person-centred approach that enhances support quality for persons with EOD and increases job satisfaction for formal care providers. Successful strategies can inform case management, strengthen support for this population and indirectly improve family caregivers' competencies.
No patient or public contribution.
COREQ (COnsolidated criteria for REporting Qualitative research).
by Darren Curnoe, Mohammed S. Sauffi, Hsiao Mei Goh, Xue-feng Sun, Roshan Peiris
The rarity of Late Pleistocene hominin remains from Insular Southeast Asia (ISEA) has hampered our ability to understand a crucial episode of human evolutionary history, namely, the global dispersal of Homo sapiens from Africa. Moreover, recent discoveries indicate a surprising level of taxic diversity during this time with at least two species—H. floresiensis and H. luzonensis—endemic to the region when H. sapiens first arrived. A third hominin dubbed the ‘Denisovans’ is shown from DNA evidence to have interbred with the ancestors of contemporary Indigenous populations across ISEA, New Guinea and Australia. Yet, the Denisovans have not been identified from the fossil record of the area despite recent breakthroughs in this regard on mainland East Asia. New excavations by our team at the Trader’s Cave in the Niah National Park (‘Niah Caves’), northern Borneo, have yielded an isolated hominin upper central permanent incisor dated with Optically Stimulated Luminescence dating of sediments to about 52 − 55 thousand years ago. Specimen SMD-TC-AA210 has a massive crown absolutely and relative to its root size, the crown is wide (mesiodistally) and relatively short (labiolingually). Morphologically, it exhibits a very strong degree of labial convexity, pronounced shovelling, and the bulging basal eminence exhibits several upward finger-like projections. Labial enamel wrinking on the enamel-dentine junction is expressed as two large ridges exhibiting numerous spine-like projections, and the lingual extensions on the enamel surface of the basal eminence are expressed as six extensions. This combination of crown size and morphological traits is not normally found in H. sapiens and instead characterises archaic members of Homo such as H. erectus, H. neanderthalensis and Middle Pleistocene hominins sharing a clade with H. heidelbergensis. The Trader’s Cave tooth suggests that an archaic hominin population inhabited northern Borneo just prior to or coincident with the arrival of H. sapiens as documented at the nearby West Mouth of the Niah Great Cave.To explore post-anaesthesia care unit nurses' perceptions and experiences in managing paediatric emergence delirium, and to understand their experiences in implementing the Cornell Assessment of Paediatric Delirium—Traditional Chinese version tool in clinical practice following delirium-focused education.
This interpretive qualitative study involved 20 nurses in the post-anaesthesia care unit from a medical centre hospital in Taiwan who participated in small group interviews after completing delirium-focused education. Data were collected through semi-structured interviews between October and December 2024 and analysed using a thematic analysis approach.
Five main themes were identified: (1) First impressions and reflexive actions during emergence delirium, (2) Clinical interpretation through observation and elimination, (3) The dual role of parents in emergence delirium management, (4) Negotiating trust and learning with the delirium screening tool and (5) System-level needs and recommendations. Nurses described the chaotic and emotionally charged nature of emergence delirium episodes, the intuitive yet uncertain interpretive work they performed, the complex influence of parental presence, evolving trust in structured assessment tools and systemic barriers that hindered timely emergence delirium recognition.
Nurses face complex clinical, emotional and relational challenges in managing paediatric emergence delirium. Embedding delirium awareness into practice requires sustained training, screening integration and proactive parental engagement.
Findings highlight the need for integrating delirium screening into post-anaesthesia care routines, the need for ongoing education and preparing parents for emergence delirium scenarios to enhance care delivery and safety.
The COREQ checklist was used for reporting.
No patient or public involvement.
FreshRSS 