The association between epicardial adipose tissue thickness and diabetes mellitus, hyperlipidemia, hepatosteatosis, pancreatic steatosis and pancreatitis

by Ece Zengin, Aybuke Ucgun, Mehmet Emir Çevik, Sehnaz Evrimler, Ihsaniye Suer Dogan

Background

Epicardial adipose tissue (EAT) is associated with cardiometabolic disorders such as diabetes mellitus (DM), hyperlipidemia, and nonalcoholic fatty liver disease. However, its potential relationship with pancreatic steatosis and pancreatitis remains unclear, and existing studies offer inconsistent findings. Therefore, a clearer understanding of whether EAT reflects broader systemic ectopic fat burden or inflammatory processes is needed.This study evaluated the relationships between EAT thickness and DM, hyperlipidemia, hepatosteatosis, pancreatic steatosis, and pancreatitis.

Methods

This retrospective, single-center study included 200 patients who underwent abdominal CT between 2022 and 2024. EAT thickness was measured at the mid-RCA and LAD levels, and subcutaneous fat was measured at the umbilical level. Liver and pancreatic steatosis were assessed with CT or MRI. Demographic and clinical data (age, gender, LDL cholesterol, diabetes, and history of pancreatitis) were collected. Mann-Whitney U, Spearman correlation, and logistic regression were used in analyses; p  Results

Of the 200 patients, 31.4% had diabetes, 42% had hepatosteatosis, and 73.5% had a history of pancreatitis. EAT and subcutaneous fat were significantly higher in women at all levels (p  Conclusions

EAT thickness is significantly associated with DM, LDL cholesterol, pancreatitis history, and age, supporting its role as a potential imaging biomarker of cardiometabolic risk. These findings suggest that EAT may serve as an imaging marker of broader metabolic and inflammatory burden, supporting its relevance for cardiometabolic risk assessment.

Supporting mental well-being of healthcare workers using a mobile app: A mixed-methods feasibility study

by Mehmet Yildirim, Timothy Carter, Holly Blake

Poor mental well-being is common among healthcare workers, affecting individual health, patient safety, and organisational performance. Mobile app-based self-care interventions are promising due to their accessibility, low cost, and ease of use. This study aimed to assess the feasibility of a self-monitoring mobile app called MYARKEO, to improve mental well-being among healthcare workers and healthcare trainees in the United Kingdom (UK). The study evaluated recruitment and retention rates, variability of key outcomes to inform a future randomised controlled trial (RCT), intervention engagement, barriers and facilitators to engagement, and potential refinements to the mobile app. A mixed-method feasibility RCT was conducted with two groups: an intervention group using MYARKEO to monitor mental well-being over 6 weeks, and a non-intervention control group. Data were collected at baseline and post-intervention and included the Warwick-Edinburgh Mental Well-being Scale (WEMWBS), the Depression Anxiety and Stress Scale (DASS-21), and the mHealth App Usability Questionnaire (MAUQ). Qualitative data were collected through semi-structured interviews (n = 13) and analysed using thematic analysis. Forty-nine participants (32 workers, 17 trainees; aged 18–60+) were included in the trial, with a 20.5% dropout rate. Daily app usage averaged 64.5%. Participants frequently monitored mood, sleep, food, and exercise. Interviews identified themes of “Usefulness,” “Enablers of engagement,” “Barriers to engagement,” and “Suggested intervention improvements.” This study demonstrates the feasibility of using a mobile app to monitor and promote mental well-being among healthcare workers and trainees. While app engagement was promising, challenges were identified, highlighting the need for refinements to the app’s content, interface, and design for future trials.

The impact of sport engagement on life satisfaction, mental and psychological well-being among athletes

by Arif Özsarı, Halil Uysal, Gültekin Lekesiz, Mehmet Çağrı Çetin, Murat Tilki, Erkan Gülgösteren, Tolga Tek, Mehmet Altın

Physical inactivity is a prevalent issue worldwide with concerning implications for public health. Regular participation in sporting activities is associated with numerous physical, psychological, and social benefits. This research aimed to examine the the impact of sport engagement on sportive life satisfaction, mental well-being, and psychological well-being among 473 Turkish athletes, comprising 246 females and 227 males, from various sports disciplines: football, rugby, wrestling, kickboxing, archery, table tennis, taekwondo, volleyball, swimming, cycling, handball, and karate. Research data were collected through validated scales measuring sport engagement, sportive life satisfaction, mental well-being, and psychological well-being. In addition to descriptive statistics, hypotheses formulated within the research model were tested via correlation and multiple regression analyses within the relational model framework. Correlation analysis demonstrated a positive association between sport engagement and all three well-being dimensions. Multiple regression analyses further confirmed that sport engagement significantly and positively predicted sportive life satisfaction, mental and psychological well-being. Sports participation should be encouraged to enhance life satisfaction, mental and psychological well-being.