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☐ ☆ ✇ International Wound Journal

The Role of Perfumes in Surgical Wound Infections and Wound Healing: A Case–Control Study

ABSTRACT

A common complication of post-surgical procedures is surgical site infections (SSIs), and wound healing can be gravely affected by these SSIs. Perfumes are known for their use in personal hygiene; however, their role in surgical wound healing and SSIs has not been thoroughly studied. The present study explores the post-operative usage of perfumes in the context of SSIs and wound healing. This was a case–control study conducted in Hail City's Tertiary Care Hospital in Saudi Arabia for 9 months (April–December). The participants were adults undergoing clean elective plastic surgeries. Sixty-three patients were divided into case (n = 31) and control (n = 32) groups; the former used perfumes continuously post-operation and the latter refrained from them. All patients were observed and followed for three follow-up periods. Data on their demography, characteristics of wounds, patterns of perfume use (Arabic, Western and mixed), and infection outcomes were collected and statistically analysed using SPSS v22 at the significance level of < 0.05. In the present study, 49.21% of the total participants kept using perfume after their surgeries. The abdomen was the most common operative site in the control (16, 32%) and case (15, 48.38%) groups. The majority of the patients in the control (15, 46.87%) and case (21, 67.74%) groups had wound size > 15 cm (p > 0.05). Amongst 31 patients in the case group, most of the patients used mixed (Arabic and Western) perfumes (12, 38.7%, p = 0.65). The frequency of perfume application varied, as most participants (11, 35.48%) reported using perfume twice daily (p = 0.49). Meanwhile, 22 (71%) used 2–4 sprays per application (p < 0.05). During the first follow-up, SSIs were only reported amongst patients in a case group (2, 6.45%, p = 0.14). During the second follow-up, SSIs were observed in 3 (9.67%) and 2 (6.25%) patients in the case and control groups, respectively (p = 0.61). Meanwhile, in the third follow-up, the SSI pattern was changed, and patients in the control group developed SSIs (p = 0.10). Furthermore, a non-significant (p > 0.05) association was observed amongst the risk factors, including age, comorbidities, perfume types, operation type, wound site and wound size with infection rates. SSIs are not significantly associated with perfume usage after surgeries, even though the rates were higher amongst the non-perfume users. Future research can explore the biochemical analyses of different perfume types and their psychophysiological effects on wound healing.

☐ ☆ ✇ PLOS ONE Medicine&Health

Intergenerational transmission of violence in Bangladesh: Mediated through maternal attitudes towards intimate partner violence, disciplinary beliefs, and life satisfaction

Por: Ahmed Usama Fahim · Atika Aboni · Shirajoom Munira · Nishat Tasnim Toosty — Enero 30th 2026 at 15:00

by Ahmed Usama Fahim, Atika Aboni, Shirajoom Munira, Nishat Tasnim Toosty

Introduction

Child discipline, while intended to instill appropriate behavior, often manifests as violent practices in low- and middle-income countries, including Bangladesh. Maternal exposure to violence, attitude towards intimate partner violence (IPV), and disciplinary beliefs serve as key determinants of physical disciplinary practices. These dynamics illustrate how exposure to violence in adulthood can shape parenting behaviors, highlighting the urgency of addressing cultural attitudes that sustain harsh physical discipline.

Materials and methods

This study analyzed nationally representative cross-sectional data from the 2019 Bangladesh Multiple Indicator Cluster Survey (MICS) which included 30044 mother-child (children aged between 2 and 14 years) pairs. Physical disciplinary practice is analyzed as an ordered outcome, considering maternal experience of physical violence as the primary exposure along with their attitudes toward IPV and disciplinary beliefs as mediators. This study used ordinal logistic regression within a structural equation modeling framework and bootstrapping technique to analyze indirect associations, providing robust inference that accounts for sampling variability and accommodates binary mediators.

Results

Mothers exposed to violence had significantly higher odds of physically disciplining their children (odds ratio, OR=1.77 and 95% confidence interval, CI=[1.60, 1.95]). Three mediators significantly increased the odds of adopting harsh physical disciplinary practice by 2% through maternal positive attitudes toward IPV, by 51% through their disciplinary beliefs, and by 6% through their overall life satisfaction. The total association indicated that maternal exposure to violence nearly tripled the odds (OR = 2.89 and 95% CI= [2.52, 3.31]) of physical disciplinary practices.

Conclusion

This study suggested that supportive environment for children can be fostered by reducing violence against women, promoting mothers’ life satisfaction, and reshaping women’s perceptions of spousal abuse and disciplinary beliefs.

☐ ☆ ✇ PLOS ONE Medicine&Health

Downregulation of serum vitamin D receptor level, serum 25-hydroxyvitamin D, and association of vitamin D receptor gene polymorphisms ApaI and TaqI with obesity in the Bangladeshi population

by Annur Ferdous, Munira Jahan Raisa, Md Hijbullah, Nafiz Imtiaz Siam, Shatabdy Barua Trisha, Sadia Biswas Mumu, Md Aminul Haque, Javed Ibne Hasan, Muhammed Mahfuzur Rahman, Md Shaki Mostaid

Background/Objectives

Obesity is a chronic metabolic disorder, and its prevalence in Bangladesh is increasing at an alarming rate. Previous reports have suggested a significant association between Vitamin D receptor (VDR) gene polymorphisms and obesity, but with inconsistent results. The purpose of our study was to investigate the association between two single-nucleotide polymorphisms (SNPs) (Apal, rs7975232, and Taql, rs731236) of the VDR gene and the risk of obesity in the Bangladeshi population. Moreover, we looked at serum VDR levels and serum 25-hydroxy vitamin D levels in people with obesity (n = 124) and healthy controls (n = 126).

Methods

Genotyping was performed using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). General linear model and multivariate logistic regression analysis were used to calculate the adjusted odds ratio (OR) along with 95% confidence intervals (CI) and P-values.

Results

Serum VDR level was downregulated in people with obesity compared to healthy controls (P  A) polymorphism, the CA Heterozygous genotype carried a 1.93-fold higher risk of developing obesity (OR=1.93, 95% CI = 1.10–3.41, P = 0.023). On the contrary, for TaqI, rs731236 (T > C), no significant association was found for both heterozygous and mutant homozygous genotypes.

Conclusion

We report the downregulation of serum VDR levels and serum 25-hydroxy vitamin D levels in people with obesity. Moreover, a polymorphism of Apal (rs7975232 C > A) in the VDR gene increases the risk of developing obesity in the Bangladeshi population.

☐ ☆ ✇ BMJ Open

Whom to include? A cross-sectional survey study investigating how culture impacts diagnostic decision making for paediatric cancer in Pakistan

Por: Graetz · D. · Wardell · J. · Hameed · A. · Tul Quanita · A. · Najmi · A. · Ahmad · S. · Shafiq · M. · Naheed · A. · Munir · S. · Ferrara · G. · Staples · C. · Chen · Y. · Devidas · M. · Rodriguez-Galindo · C. · Jeha · S. · Mack · J. · Hamid · S. A. · Rafie Raza · M. · Ahmad · A. — Noviembre 6th 2025 at 06:00
Objectives

This study sought to explore decision making among caregivers of children with cancer in Pakistan, one of the largest lower middle-income countries in the world.

Design

Cross-sectional survey study

Setting

This study was conducted in Pakistan at Indus Hospital and Health Network in Karachi and Children’s Hospital of Lahore. Children’s Hospital of Lahore is a public sector hospital, and Indus Hospital has a foundation-based funding structure. Both are larger tertiary care centers. Over 2,500 new patients are seen at these centers annually, this accounts for almost 50% of all children with cancer in Pakistan

Participants

Eligible participants included bedside caregivers, defined as a parent or family member involved in communication with the medical team, of children with cancer (

Primary and secondary outcome measures

Primary outcome measures included caregiver priorities and experiences related to communication including decision-making role, involvement of the paediatric patient and decisional regret.

Results

Participants included 200 caregivers of children

Conclusions

Findings from this study highlight the importance of exploring preferences for decision making and empowering bedside caregivers while respecting cultural norms. In the Pakistani context, it may be specifically important to consider gender roles and the inclusion of extended family members. Future work should investigate paediatric patient involvement in diverse settings.

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