The Chronic Disease Self-Management Program (CDSMP) is a widely used peer-led patient education intervention that imparts disease knowledge and self-management skills to people with chronic diseases. While the CDSMP was developed to be accessible to people with diverse chronic diseases, chronic disease self-management needs and beliefs can vary by clinical or cultural populations. Questions remain regarding the range of populations it has been adapted for and the methods that have been used to make these modifications. This scoping review explores the following research questions: For which clinical and cultural populations has the CDSMP been adapted? Which methods, frameworks and/or processes have been used to inform CDSMP adaptations?

We are conducting a scoping review with guidance from the JBI Manual for Evidence Synthesis and Arksey and O’Malley’s framework. Search results were retrieved on 30 October 30 and 4 November 2025 from the following databases: Medline (Ovid) 1946–2025, Embase (Elsevier) 1974–2025, CINAHL Complete (Ebscohost) 1937–2025, Cochrane CENTRAL (Wiley) 1898–2025, Web of Science Core Collection (Clarivate) 1900–2025, Sociological Abstracts (ProQuest) 1952–2025, Dissertations and Theses Global (ProQuest) 1861–2025 and Dimensions (Digital Science) coverage varies. Conference abstracts were excluded from Embase, Web of Science, Sociological Abstracts and Dimensions. Additionally, chapter, edited book, monograph, reference work and research chapters were excluded in Dimensions.

Inclusion criteria encompass any study type reporting on adaptations to the CDSMP and include people of any age diagnosed with any chronic disease, and specifically asthma, arthritis, cancer, cardiovascular disease, diabetes, heart disease, hypertension or stroke, who are attending the CDSMP in any type of health setting. Data will be extracted and organised into categories and subthemes in tabular form. To extract information on adaptations, we will use an adapted version of the Framework for Reporting Adaptations and Modifications.

This study does not involve the participation of human subjects. Thus, we do not have approval from an Institutional Review Board. Review findings will be disseminated through a peer-reviewed journal and at conferences. This protocol is registered with Open Science Framework (https://doi.org/10.17605/OSF.IO/27KTF).