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☐ ☆ ✇ BMJ Open

Feasibility of an AI-assisted transcranial duplex sonography protocol for early detection of intracerebral haemorrhage: the HYPER-AI-SCAN single-centre prospective study

Por: Simonetti · R. · Canals · P. · Gonzalez Riveros · J. D. · Alanis-Bernal · M. · Pancorbo · O. · Rodriguez-Luna · D. — Noviembre 20th 2025 at 07:42
Introduction

Intracerebral haemorrhage (ICH) is associated with high early mortality and morbidity. Early clinical deterioration is common and influenced by haematoma expansion, which can occur within the first hours after symptom onset. Transcranial duplex sonography (TCD) is a rapid, non-invasive tool that may aid in early ICH detection but is highly operator-dependent. Artificial intelligence (AI)-based analysis of ultrasound images has shown promise in other fields but has not yet been validated in acute ICH.

Methods and analysis

This is a single-centre, prospective feasibility study involving 500 patients with acute ischaemic and haemorrhagic stroke (

Ethics and dissemination

Ethical approval has been obtained. Informed consent will be collected. Data will be coded and stored securely. Results will be disseminated through peer-reviewed journals and conferences.

Trial registration number

Not applicable at this stage (observational AI study).

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