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This study aimed to evaluate the ability of three generative artificial intelligence tools (ChatGPT, Gemini and DeepSeek) to generate clinically accurate, comprehensive, and readable nursing care plans aligned with standardised nursing taxonomies (North American Nursing Diagnosis Association International, Nursing Interventions Classification, and Nursing Outcomes Classification). The study further explored variations in tool performance across different nursing specialties.
A descriptive comparative design was used.
Ten expert-validated clinical scenarios representing five nursing specialties (Fundamentals of Nursing, Medical, Surgical, Paediatric and Psychiatric Nursing) were presented to the three artificial intelligence tools. Each tool responded to four standardised prompts based on the latest North American Nursing Diagnosis Association International, Nursing Interventions Classification and Nursing Outcomes Classification taxonomies. Outputs were assessed for quality, accuracy, completeness and readability by expert evaluators using validated scales.
All tools produced nursing care plans of moderate-to-high quality. DeepSeek demonstrated slightly higher accuracy and completeness compared with Gemini and ChatGPT. Surgical nursing scenarios yielded the highest performance, likely reflecting the more protocolised and pathway-driven nature of perioperative care. However, all outputs were incomplete and written at a college-level readability, limiting accessibility for clinical use.
Generative artificial intelligence tools can support the production of structured nursing care plans requiring expert review and adaptation, particularly in less standardised clinical domains, but their limitations in completeness and readability indicate they should be regarded only as preliminary drafts requiring expert review and adaptation.
The study examined whether generative artificial intelligence can reliably assist in creating nursing care plans. All tools performed moderately well, with DeepSeek showing slight advantages, but outputs were incomplete and difficult to read. Findings are relevant to clinical nurses, educators, healthcare managers and policymakers worldwide who are exploring artificial intelligence in nursing workflows.
This study adhered to the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines.
This study did not include patient or public involvement in its design, conduct or reporting.
by Ugur Yilmaz, Huseyin Celik, Pinar Arpinar-Avsar
This study examined how time pressure influences lower-limb biomechanics during single-leg maximal countermovement jumps (CMJs), with a focus on kinetic and kinematic responses during both jumping and landing phases. Participants performed single-leg CMJs under two conditions: self-paced (SP) and reaction-time (RT), the latter simulating time-constrained environments. Joint angles, ground reaction forces (vGRF), and joint moments were analyzed. Significant differences emerged between SP and RT tasks in jumping-phase kinetics and kinematics, with only kinematic differences present during landing. The RT condition led to reduced hip and knee flexion, increased peak vGRF, and shorter flight times, yet no improvement in jump height. This suggests inefficient energy transfer possibly due to reduced range of motion and increased muscle co-contraction or pretension strategies. Joint moment analysis revealed a shift from a hip-dominant strategy in SP to a knee-dominant strategy in RT. Landing in RT was characterized by reduced joint flexion and increased frontal plane loading, potentially elevating the risk of lower-limb injury. Time pressure modifies motor strategies in single-leg CMJs, promoting faster execution at the cost of performance efficiency. These findings underscore the importance of training for both explosive performance and neuromuscular control under time-constrained, sport-specific conditions.
by Wenshu Li, Jeffrey A. Leibowitz, Shuoguo Wang, Louisa Walker, Chang Xu, Kuei-Ting Chen, Alexa B. Schrock, Jason Hughes, Nimesh Patel, Julia A. Elvin, Lauren L. Ritterhouse, Ethan Sokol, Garrett Frampton, Lucas Dennis, Bahar Yilmazel, Brennan Decker
Homologous recombination repair (HRR) is a cellular pathway for high-fidelity double strand DNA break repair that uses the sister chromatid as a guide to ensure chromosomal integrity and cell viability. Deficiency in the HRR pathway (HRD) can sensitize tumors to poly (ADP-ribose) polymerase inhibitors (PARPi) and platinum-based chemotherapy, offering an avenue to identify patients who may benefit from targeted therapies. HRD signature (HRDsig) is a pan-solid-tumor biomarker on the FoundationOne®CDx (F1CDx®) assay that employs a DNA scar-based approach to calculate a score based on copy number features (e.g., segment size, oscillation patterns, and breakpoints per chromosome arm) and does not rely on HRR gene alterations, enabling detection of genomic and epigenetic mechanisms of HRD. After finalizing the HRDsig algorithm, analytical validation was conducted in a CAP-accredited, CLIA-certified laboratory on 278 solid tumor and normal tissue specimens. HRDsig results were compared with an independent HRD biomarker, defined by the presence of a reversion mutation restoring HRR gene function. In this evaluation, 100 HRD-positive and 126 HRD-negative samples showed a positive percent agreement of 90.00% and a negative percent agreement of 94.44%. The limit of detection (LoD) was estimated at 23.04% tumor purity, with the limit of blank (LoB) confirmed as zero in 60 normal tissue replicates. Reproducibility testing on 11 positive and 11 negative samples across multiple labs, reagent lots, and sequencers yielded agreement in 99.49% of positive and 99.73% of negative replicates. HRDsig status remained consistent in the presence of interfering substances, demonstrating 100% concordance in spiked samples. These validation results underscore the high analytical concordance, low false-positive rate, and overall robustness of HRDsig for reliable assessment of homologous recombination deficiency.
Children with special needs frequently experience accidents and injuries due to motor control difficulties. The most common home accidents include falls, burns, poisoning, drowning and choking. Compared to their typically developing peers, children with special needs are at a higher risk of home accidents and emergency department visits. Falls related to balance impairments are especially common in this population. The aim of this study is to assess the effects of a virtual reality-based home accident control simulation combined with first aid training on the awareness and initial responses to home accidents of parents of children with special needs, using a single-group pre-post quasi-experimental design.
This quasi-experimental study, using a pre-test/post-test design, is planned to include 100 volunteer parents of children with special needs who are registered at a Barrier-Free Life Application and Research Centre. The parents will receive training on home accidents via virtual reality simulation, supplemented by first aid and transfer training. Data will be collected using the Descriptive Information Form and the Home Accident Awareness Questionnaire for Parents of Children with Special Needs. Children’s balance status will be assessed to determine their fall risk using the Children’s Balance Assessment Form, the Tinetti Balance and Gait Assessment and the Nintendo Wii Fit Balance Board.
Ethical approval was obtained from the Ethics Committee of Istanbul Topkapi University. The results will be disseminated through peer-reviewed journals and academic conferences.
NCT06839196 (ClinicalTrials.gov). Protocol version: 1.2; Protocol Date: 30 April 2025. All items from the WHO Trial Registration Data Set are available in the registry record.
The aim of this study was to investigate the effect of postoperative thirst on patient comfort and quality of recovery in patients undergoing colorectal surgery.
This study is an analytical cross-sectional study.
This study was conducted between July 2022 and January 2023 in the general surgery clinics of a university hospital in Ankara, Türkiye. The study sample consisted of 110 patients. Patient Identification Form, Thirst Symptom Assessment Scale (TSAS), Numeric Rating Scale (NRS), Perianesthesia Comfort Scale (PCS) and Quality of Recovery-40 questionnaire (QoR-40) were used for data collection. The severity of thirst was assessed three times: at the time of arrival to the postoperative clinic, at the 8th hour, and at the 24th hour, and the PCS and QoR-40 scales were administered at the 24th hour.
In this study, more than half of the patients were male (62.7%) and the mean age was 61.35 ± 13.79 years. The mean thirst severity of the patients was 12.25 ± 4.65, 12.36 ± 4.49 and 11.27 ± 4.76 according to the TSAS, 7.27 ± 2.39, 7.27 ± 2.01 and 6.17 ± 2.89 according to the NRS, respectively. The mean total score of PCS was 5.12 ± 0.43 and the mean total score of QoR-40 was 171.58 ± 10.33. Postoperative 8th hour thirst severity according to NRS, PCS total score level and postoperative thirst severity measured by TSAS at three times were found to have a significant effect on QoR-40 total score level in a decreasing direction. PCS total score was found to have a significant effect on QoR-40 total score level in an increasing direction.
The results obtained in this study showed that the thirst symptom experienced by the patients was moderate. It was determined that an increase in the severity of thirst decreased patients' comfort and quality of recovery levels, whereas an increase in comfort level increased the level of quality of recovery.
It is recommended that the severity of thirst should be assessed frequently with appropriate scales and appropriate nursing care should be provided for thirst management in order to increase the postoperative comfort of patients and to improve their recovery more positively.
No study has been found to describe and compare the effect of postoperative thirst on comfort and quality of recovery in patients undergoing colorectal surgery. In this study, it was found that an increase in the severity of postoperative thirst decreased the level of postoperative comfort and quality of recovery, whereas an increase in the level of postoperative comfort increased the level of quality of recovery. This information can be used to optimally manage the symptom of thirst after colorectal surgery, develop evidence-based nursing interventions, and improve the quality of care.
This study was reported according to the STROBE checklist.
Patients answered the scales with their voluntary consent. There is no public contribution.
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